⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760453 | 1.00 | — | — | |
| SCHEMBL8761365 | 1.00 | — | — | |
| SCHEMBL8761354 | 1.00 | — | — | |
| SCHEMBL8761317 | 1.00 | — | — | |
| SCHEMBL9223793 | 0.82 | — | — | |
| SCHEMBL6053170 | 0.81 | LMNA (0.41) | — | |
| SCHEMBL9854993 | 0.80 | PRKCA (0.47) | — | |
| SCHEMBL31635602 | 0.78 | — | — | |
| SCHEMBL8381538 | 0.76 | TSHR (0.41) | — | |
| SCHEMBL535005 | 0.76 | LMNA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612721-B1 | Aliphatic omega-hydroxy-3-ketonitriles and process for the preparation of aliphatic omega-hydroxycarboxylic acids | UBE INDUSTRIES (JP) | 1997-04-23 | — | — | EP | claimed |
| US-5350868-A | ω-hydroxy-(ω-3)-ketonitrile and method for preparing ω-hydroxyaliphatic acid | UBE INDUSTRIES, LTD. (JP) | 1994-09-27 | — | — | US | claimed |
| EP-0402063-B1 | Alpha-(omega-cyanoalkanoyl)-gamma-butyrolactone and method for producing the same | UBE INDUSTRIES (JP) | 1994-09-21 | — | — | EP | claimed |
| EP-0612721-A1 | Aliphatic omega-hydroxy-3-ketonitriles and process for the preparation of aliphatic omega-hydroxycarboxylic acids | UBE INDUSTRIES, LTD. (JP) | 1994-08-31 | — | — | EP | claimed |
| US-5099036-A | Reaction of butyrolactone with cyano fatty acid ester in the persence of alkali metal alcoholate | UBE INDUSTRIES, LTD. (JP) | 1992-03-24 | — | — | US | claimed |
| US-5023351-A | α-(ω-cyanoalkanoyl-γ-butyrolactone and method for producing the same | UBE INDUSTRIES, LTD. (JP) | 1991-06-11 | — | — | US | claimed |
| JP-3011046-A | — | — | None | — | — | JP | disclosed |
| US-6222049-B1 | AS MATERIAL FOR PREPARING MUSK ODOR | TORAY INDUSTRIES (JP) | 2001-04-24 | — | — | US | disclosed |
| EP-0794182-B1 | PROCESS FOR PRODUCING 2-OMEGA-ALKOXYCARBONYLALKANOYL)-4-BUTANOLIDE AND LONG-CHAIN OMEGA-HYDROXY CARBOXYLIC ACID | TORAY INDUSTRIES (JP) | 2000-11-08 | — | — | EP | disclosed |
| US-5808106-A | REACTION OF A CARBOXYLIC ACID DIESTER WITH G-BUTYROLACTONE | TORAY INDUSTRIES, INC., A CORPORATION OF JAPAN (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0794182-A1 | PROCESS FOR PRODUCING 2-($g(v)-ALKOXYCARBONYLALKANOYL)-4-BUTANOLIDE AND LONG-CHAIN $g(v)-HYDROXY CARBOXYLIC ACID | TORAY INDUSTRIES, INC. (JP) | 1997-09-10 | — | — | EP | disclosed |
| EP-0612721-B1 | Aliphatic omega-hydroxy-3-ketonitriles and process for the preparation of aliphatic omega-hydroxycarboxylic acids | UBE INDUSTRIES (JP) | 1997-04-23 | — | — | EP | disclosed |
| US-5380912-A | ω-hydroxy-(ω-3)-ketonitrile | UBE INDUSTRIES, LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| US-5350868-A | ω-hydroxy-(ω-3)-ketonitrile and method for preparing ω-hydroxyaliphatic acid | UBE INDUSTRIES, LTD. (JP) | 1994-09-27 | — | — | US | disclosed |
| EP-0402063-B1 | Alpha-(omega-cyanoalkanoyl)-gamma-butyrolactone and method for producing the same | UBE INDUSTRIES (JP) | 1994-09-21 | — | — | EP | disclosed |
| EP-0612721-A1 | Aliphatic omega-hydroxy-3-ketonitriles and process for the preparation of aliphatic omega-hydroxycarboxylic acids | UBE INDUSTRIES, LTD. (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-5099036-A | Reaction of butyrolactone with cyano fatty acid ester in the persence of alkali metal alcoholate | UBE INDUSTRIES, LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| US-5023351-A | α-(ω-cyanoalkanoyl-γ-butyrolactone and method for producing the same | UBE INDUSTRIES, LTD. (JP) | 1991-06-11 | — | — | US | disclosed |
| JP-H0311046-A | ALPHA-(OMEGA-CYANOALKANOYL)-GAMMA-BUTYROLACTONE AND PREPARATION THEREOF | UBE IND LTD | 1991-01-18 | — | — | JP | disclosed |
| EP-0402063-A2 | Alpha-(omega-cyanoalkanoyl)-gamma-butyrolactone and method for producing the same | UBE INDUSTRIES, LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |