Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 8/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042523 | 0.73 | PDE10A (0.44) | PDE10APDE4DALDH1A1MAPT | |
| SCHEMBL510059 | 0.67 | PDE4A (0.59) | PDE4DPDE4A | |
| SCHEMBL509400 | 0.64 | PDE4A (0.61) | PDE4DPDE4A | |
| SCHEMBL508221 | 0.63 | PDE4D (0.59) | PDE4DPDE4A | |
| SCHEMBL17571398 | 0.63 | PDE4D (0.48) | PDE4DPDE4A | |
| SCHEMBL3469402 | 0.62 | PDE4A (0.58) | PDE4DPDE4A | |
| SCHEMBL8298141 | 0.61 | ALDH1A1 (0.60) | ALDH1A1LMNATP53MAPTALOX12 | |
| SCHEMBL22350120 | 0.58 | ALDH1A1 (0.46) | ALDH1A1LMNATP53MAPTALOX12 | |
| SCHEMBL260564 | 0.58 | PDE10A (0.56) | PDE10A | |
| SCHEMBL9963706 | 0.58 | ALDH1A1 (0.49) | ALDH1A1LMNATP53MAPTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069322-A1 | TRIAZOLOPYRIDINES AS PHOSPHODIESTERASE INHIBITORS FOR TREATMENT OF DERMAL DISEASES | LEO PHARMA A/S (DK) | 2010-06-24 | — | — | WO | disclosed |