Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939275 | 0.96 | GAA (0.60) | GAATSHRMAPK1L3MBTL1TP53 | |
| SCHEMBL7939446 | 0.95 | GAA (0.59) | GAATSHRMAPK1L3MBTL1TP53 | |
| SCHEMBL13831908 | 0.88 | TP53 (0.65) | GAAL3MBTL1TP53POLBLMNA | |
| SCHEMBL7941803 | 0.87 | TP53 (0.57) | GAATP53POLBLMNAMAPT | |
| SCHEMBL13831362 | 0.84 | TDP1 (0.59) | GAATSHRL3MBTL1TP53POLB | |
| SCHEMBL13856863 | 0.83 | TP53 (0.55) | TP53POLBLMNAMEN1KMT2A | |
| SCHEMBL20682668 | 0.82 | GAA (0.71) | GAATSHRMAPK1TP53POLB | |
| SCHEMBL4198392 | 0.81 | LMNA (0.84) | GAATSHRMAPK1L3MBTL1TP53 | |
| SCHEMBL15983367 | 0.81 | NPC1 (0.54) | GAATSHRTP53POLBLMNA | |
| SCHEMBL13831511 | 0.80 | TP53 (0.53) | GAATSHRTP53POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245817-B1 | NEUROPEPTIDE Y | BAYER CORPORATION | 2001-06-12 | — | — | US | claimed |