Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.54 |
| ▸ | S100A10 | P60903 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13831908 | 0.93 | TP53 (0.65) | TP53RAB9ASMN1; SMN2MAPTALOX15 | |
| SCHEMBL7939446 | 0.92 | GAA (0.59) | TP53RAB9ASMN1; SMN2MAPTALOX15 | |
| SCHEMBL7939275 | 0.91 | GAA (0.60) | TP53MAPTALOX15LMNAALDH1A1 | |
| SCHEMBL13856863 | 0.88 | TP53 (0.55) | TP53RAB9ASMN1; SMN2MAPTALOX15 | |
| SCHEMBL13831362 | 0.87 | TDP1 (0.59) | TP53SMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL7930229 | 0.87 | GAA (0.64) | TP53MAPTALOX15LMNAALDH1A1 | |
| SCHEMBL15986095 | 0.87 | LMNA (0.67) | TP53RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL13832011 | 0.85 | ALDH1A1 (0.61) | TP53SMN1; SMN2MAPTLMNAALDH1A1 | |
| SCHEMBL15983367 | 0.85 | NPC1 (0.54) | TP53RAB9ASMN1; SMN2MAPTALOX15 | |
| SCHEMBL13831511 | 0.83 | TP53 (0.53) | TP53RAB9ASMN1; SMN2MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245817-B1 | NEUROPEPTIDE Y | BAYER CORPORATION | 2001-06-12 | — | — | US | claimed |