SCHEMBL7930378

SCHEMBL7930378

CCOC(=O)/C(Cl)=C/c1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)ccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BCAT1 P54687 12/20 0.42
BCAT2 O15382 10/20 0.42
MAPT P10636 3/20 0.38
TSHR P16473 2/20 0.37
ALDH1A1 P00352 2/20 0.37
HSD17B10 Q99714 3/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7930382 1.00 BCAT1 (0.42) BCAT1BCAT2MAPTTSHRALDH1A1
SCHEMBL7927757 0.85 BCAT1 (0.42) BCAT1BCAT2MAPTTSHRALDH1A1
SCHEMBL7927759 0.85 BCAT1 (0.42) BCAT1BCAT2MAPTTSHRALDH1A1
SCHEMBL7921775 0.81 ALDH1A1 (0.34) MAPTALDH1A1SMN1; SMN2HTT
SCHEMBL7933742 0.81 ALDH1A1 (0.38) MAPTTSHRALDH1A1HSD17B10SMN1; SMN2
SCHEMBL7933744 0.81 ALDH1A1 (0.38) MAPTTSHRALDH1A1HSD17B10SMN1; SMN2
SCHEMBL7921773 0.81 ALDH1A1 (0.34) MAPTALDH1A1SMN1; SMN2HTT
SCHEMBL23635730 0.80 BCAT1 (0.40) BCAT1BCAT2MAPTTSHRALDH1A1
SCHEMBL7973578 0.79 BCAT1 (0.43) BCAT1BCAT2MAPTTSHRALDH1A1
SCHEMBL8112922 0.79 BCAT1 (0.44) BCAT1BCAT2ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010031865-A1 Substituted 3-phenyluracils KLINTZ RALF (DE) 2001-10-18 US disclosed
US-6239074-B1 HERBICIDES, INSECTICIDES BASF AKTIENGESELLSCHAFT (DE) 2001-05-29 US disclosed
EP-0604491-A1 SUBSTITUTED 3-PHENYLURACILS AS HERBICIDES BASF Aktiengesellschaft (DE) 1994-07-06 EP disclosed
WO-1993006090-A1 SUBSTITUTED 3-PHENYLURACILS AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1993-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031865-A1 Substituted 3-phenyluracils CCR1, CCR6, CCR3 BCAT1 139/4885BCAT2 599/4885MAPT 4647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.