SCHEMBL7930494

SCHEMBL7930494

O=P(O)(O)c1ccc(O)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
POLB P06746 1/20 0.42
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA5A P35218 1/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
CYP2D6 P10635 1/20 0.39
HSD17B1 P14061 1/20 0.39
CYP2B6 P20813 1/20 0.39
HSD17B2 P37059 1/20 0.39
MAPT P10636 2/20 0.37
HTT P42858 2/20 0.37
LMNA P02545 1/20 0.37
ALOX5 P09917 1/20 0.36
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL28392022 0.86 ESR2 (0.46) KDM4ECA2CA4CA5AESR1
Phosphoric Acid SCHEMBL5946352 0.86 ESR2 (0.46) KDM4ECA2CA4CA5AESR1
SCHEMBL1760592 0.78 ESR2 (0.53) KDM4EPOLBCA2CA4CA5A
SCHEMBL6846287 0.78 KDM4E (0.44) KDM4EPOLBCA2CA4CA5A
Phosphoric Acid SCHEMBL28476358 0.77 BACE1 (0.45) ESR1ESR2CYP1A2CYP3A4CYP2C9
Phosphoric Acid SCHEMBL27657596 0.75 HDAC4 (0.47) CA2CA4CA5ACYP1A2CYP3A4
Phosphoric Acid SCHEMBL14939153 0.75 HDAC4 (0.47) CA2CA4CA5ACYP1A2CYP3A4
SCHEMBL29068817 0.74 POLB (0.40) KDM4EPOLBCA2CA4CA5A
SCHEMBL3887564 0.74 PTPN5 (0.40) KDM4EPOLBCA2CA4CA5A
Biphenyl SCHEMBL28050797 0.74 CYP1A2 (0.50) KDM4EPOLBCA2CA4CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1125984-A1 Aromatic polycarbonate-styrene polymer resin composition Asahi Kasei Kabushiki Kaisha (JP) 2001-08-22 EP disclosed
US-6069206-A COMPATIBILITY AGENT COMPRISING SPECIFIED COPOLYMER OF AROMATIC VINYL MONOMER AND POLYMERIZABLE MONOMER ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2000-05-30 US disclosed
US-5900446-A CONTAINING A COMPATIBILITY AGENT; ADDITION-CONDENSATION COPOLYMER ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1999-05-04 US disclosed
EP-0767215-A1 AROMATIC POLYCARBONATE-STYRENE POLYMER RESIN COMPOSITION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1997-04-09 EP disclosed