SCHEMBL7930620

SCHEMBL7930620

CCCCNc1c(F)c2c(c(F)c1Nc1ccc(OC)cc1)C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.45
HDAC1 Q13547 2/20 0.45
HDAC2 Q92769 2/20 0.45
HDAC10 Q969S8 1/20 0.45
HDAC11 Q96DB2 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
HDAC5 Q9UQL6 1/20 0.45
MAPT P10636 4/20 0.41
GAA P10253 3/20 0.41
MEN1 O00255 3/20 0.41
ALDH1A1 P00352 3/20 0.41
KMT2A Q03164 3/20 0.41
MAPK1 P28482 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 1/20 0.41
APAF1 O14727 1/20 0.41
TDP2 O95551 1/20 0.41
THRB P10828 1/20 0.41
CASP6 P55212 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7921288 0.87 MAPT (0.46) MAPTGAAMEN1ALDH1A1KMT2A
SCHEMBL7930584 0.86 HDAC1 (0.40) HDAC1MAPTMEN1ALDH1A1KMT2A
SCHEMBL7921197 0.82 MAPT (0.43) MAPTGAAMEN1ALDH1A1KMT2A
SCHEMBL7933255 0.81 CYP19A1 (0.46) MAPTMEN1ALDH1A1KMT2AMAPK1
SCHEMBL7933097 0.79 CYP19A1 (0.47) MAPTMEN1ALDH1A1KMT2AMAPK1
SCHEMBL7927279 0.77 ADAMTS5 (0.44) MAPTMEN1ALDH1A1KMT2AMAPK1
SCHEMBL7921285 0.76 ADAMTS5 (0.40) MAPTGAAMEN1ALDH1A1KMT2A
SCHEMBL7921400 0.76 HPGD (0.52) MAPTMEN1ALDH1A1KMT2AMAPK1
SCHEMBL7930019 0.76 ADAMTS5 (0.46) ADAMTS5
SCHEMBL7928292 0.76 SMN1; SMN2 (0.49) MAPTALDH1A1KMT2AKDM4ETHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5968688-A RESINS AND DYES FOR COLOR FILTERS NIPPON SHOKUBAI CO., LTD. (JP) 1999-10-19 US disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
EP-0833203-A1 Color filter grade photosensitive resin coloring composition, and color filter using the same NIPPON SHOKUBAI CO., LTD. (JP) 1998-04-01 EP disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed