SCHEMBL793065

SCHEMBL793065

CC1(C)OB(c2ccc(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)nc2)OC1(C)C

nearest known ligand 0.63

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 2/20 0.63
LIPG Q9Y5X9 13/20 0.51
LPL P06858 12/20 0.51
CYP11B1 P15538 1/20 0.41
PDGFRB P09619 1/20 0.39
KDR P35968 1/20 0.39
P4HB P07237 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15498061 0.99 DGAT1 (0.62) DGAT1LIPGLPLCYP11B1PDGFRB
SCHEMBL15498062 0.90 DGAT1 (0.54) DGAT1LIPGLPLPDGFRBKDR
SCHEMBL15498027 0.88 DGAT1 (0.53) DGAT1LIPGLPLPDGFRBKDR
SCHEMBL18015662 0.88 DGAT1 (0.70) DGAT1LIPGLPLCYP11B1PDGFRB
SCHEMBL29688361 0.87 DGAT1 (0.70) DGAT1LIPGLPLCYP11B1PDGFRB
SCHEMBL30739 0.87 DGAT1 (0.70) DGAT1LIPGLPLCYP11B1PDGFRB
SCHEMBL15498081 0.87 DGAT1 (0.53) DGAT1LIPGLPLCYP11B1PDGFRB
SCHEMBL15747808 0.86 DGAT1 (0.69) DGAT1LIPGLPLPDGFRBKDR
SCHEMBL21125909 0.86 DGAT1 (0.67) DGAT1LIPGLPLPDGFRBKDR
SCHEMBL12094234 0.83 DGAT1 (0.46) DGAT1LIPGLPLCYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2681970-B1 POROUS FILMS FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORP (JP) 2018-01-17 EP disclosed
EP-2616457-B1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES NITTO DENKO CORP (JP) 2016-06-22 EP disclosed
EP-2616457-B1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES NITTO DENKO CORP (JP) 2016-06-22 EP disclosed
US-9328086-B2 Substituted bipyridines for use in organic light-emitting devices NITTO DENKO CORPORATION (JP) 2016-05-03 US disclosed
US-9328086-B2 Substituted bipyridines for use in organic light-emitting devices NITTO DENKO CORPORATION (JP) 2016-05-03 US disclosed
US-9328086-B2 Substituted bipyridines for use in organic light-emitting devices NITTO DENKO CORPORATION (JP) 2016-05-03 US disclosed
US-9172051-B2 Organic light emitting host materials NITTO DENKO CORPORATION (JP) 2015-10-27 US disclosed
US-9172051-B2 Organic light emitting host materials NITTO DENKO CORPORATION (JP) 2015-10-27 US disclosed
US-9172051-B2 Organic light emitting host materials NITTO DENKO CORPORATION (JP) 2015-10-27 US disclosed
US-20140066627-A1 ORGANIC LIGHT EMITTING HOST MATERIALS NITTO DENKO CORPORATION (JP) 2014-03-06 US disclosed
EP-2616457-A1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES Nitto Denko Corporation (JP) 2013-07-24 EP disclosed
WO-2012119111-A1 POROUS FILMS FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-09-07 WO disclosed
WO-2012119111-A1 POROUS FILMS FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-09-07 WO disclosed
US-20120223635-A1 POROUS FILMS FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-09-06 US disclosed
US-20120223635-A1 POROUS FILMS FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-09-06 US disclosed
US-20120179089-A1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-07-12 US disclosed
US-20120179089-A1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-07-12 US disclosed
US-20120179089-A1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-07-12 US disclosed
WO-2012037269-A1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-03-22 WO disclosed
WO-2012037269-A1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120179089-A1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES BRD9, PIR, BRD2 DGAT1 4753/4885LIPG 4627/4885LPL 3491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.