Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 6/20 | 0.47 |
| ▸ | THRB | P10828 | 6/20 | 0.47 |
| ▸ | MAOB | P27338 | 5/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3704809 | 0.89 | KDM4E (0.59) | KDM4EMAPTHPGDHSD17B10MAOB | |
| SCHEMBL787766 | 0.86 | MAPT (0.61) | KDM4EMAPTHTTHPGD | |
| SCHEMBL30134679 | 0.86 | MAPT (0.61) | KDM4EMAPTHTTHPGD | |
| SCHEMBL787535 | 0.83 | MAPT (0.56) | KDM4EMAPTMAOB | |
| SCHEMBL30777576 | 0.83 | MAPT (0.56) | KDM4EMAPTMAOB | |
| SCHEMBL13856728 | 0.81 | HTT (0.60) | HTTTHRATHRBMAOBPLA2G2A | |
| SCHEMBL3703417 | 0.81 | KDM4E (0.53) | KDM4EMAPTHTT | |
| SCHEMBL4568616 | 0.80 | KDM4E (0.52) | KDM4EMAPTMAOB | |
| SCHEMBL933781 | 0.78 | KDM4E (0.51) | KDM4EMAPTHTTHPGD | |
| SCHEMBL3698715 | 0.77 | KDM4E (0.51) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130302497-A1 | Taste Enhancement | GIVAUDAN S.A. (CH) | 2013-11-14 | — | — | US | disclosed |
| EP-2615930-A2 | TASTE ENHANCEMENT | Givaudan SA (CH) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035032-A2 | TASTE ENHANCEMENT | GIVAUDAN SA (CH) | 2012-03-22 | — | — | WO | disclosed |