SCHEMBL787766

SCHEMBL787766

COc1ccc(C(=O)CCc2ccccn2)c(O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.61
KDM4E B2RXH2 1/20 0.61
NPC1 O15118 6/20 0.52
RAB9A P51151 6/20 0.52
PKM P14618 1/20 0.52
HPGD P15428 4/20 0.51
CYP3A4 P08684 3/20 0.51
LMNA P02545 2/20 0.51
CYP1A2 P05177 2/20 0.51
PGR P06401 2/20 0.51
SLC6A2 P23975 2/20 0.51
CYP2C19 P33261 2/20 0.51
ADORA3 P0DMS8 1/20 0.51
AR P10275 1/20 0.51
CHRM1 P11229 1/20 0.51
ALOX15 P16050 1/20 0.51
TBXA2R P21731 1/20 0.51
ADRA1A P35348 1/20 0.51
HIF1A Q16665 1/20 0.51
KMT2A Q03164 5/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30134679 1.00 MAPT (0.61) MAPTKDM4ENPC1RAB9APKM
SCHEMBL3704809 0.90 KDM4E (0.59) MAPTKDM4ENPC1RAB9APKM
SCHEMBL30777576 0.87 MAPT (0.56) MAPTKDM4ENPC1RAB9APKM
SCHEMBL787535 0.87 MAPT (0.56) MAPTKDM4ENPC1RAB9APKM
SCHEMBL3703417 0.87 KDM4E (0.53) MAPTKDM4ERAB9APKMLMNA
SCHEMBL793083 0.86 KDM4E (0.55) MAPTKDM4EHPGDHTT
SCHEMBL933781 0.84 KDM4E (0.51) MAPTKDM4ENPC1RAB9AHPGD
SCHEMBL4568616 0.83 KDM4E (0.52) MAPTKDM4ECYP1A2CYP2C19ALDH1A1
SCHEMBL3698715 0.83 KDM4E (0.51) MAPTKDM4ENPC1RAB9AKMT2A
SCHEMBL1733676 0.81 CYP19A1 (0.55) MAPTKDM4EHPGDCYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250212873-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-07-03 US claimed
EP-2742983-B1 Method for isolating fragrance and flavour compounds SYMRISE AG (DE) 2017-08-23 EP claimed
US-9173424-B2 Pyridine derivatives with umami flavour GIVAUDAN S.A. (CH) 2015-11-03 US claimed
US-9144248-B2 Cinnamamides as savory flavorings SYMRISE AG (DE) 2015-09-29 US claimed
US-20140295045-A1 Pyridine Derivatives With Umami Flavour GIVAUDAN S.A. (CH) 2014-10-02 US claimed
EP-2742983-A1 Method for isolating fragrance and flavour compounds Symrise AG (DE) 2014-06-18 EP claimed
EP-2451781-B1 PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR GIVAUDAN SA (CH) 2013-09-18 EP claimed
EP-2529632-B1 Cinnamic acid amides as spicy flavour agents SYMRISE AG (DE) 2013-08-28 EP claimed
US-20120308703-A1 Cinnamamides as savory flavorings SYMRISE AG (DE) 2012-12-06 US claimed
EP-2529632-A1 Cinnamic acid amides as spicy flavour agents Symrise AG (DE) 2012-12-05 EP claimed
US-20120121783-A1 Pyridine Derivatives With Umami Flavour GIVAUDAN SA (CH) 2012-05-17 US claimed
EP-2451781-A1 PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR Givaudan SA (CH) 2012-05-16 EP claimed
WO-2011004016-A1 PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR GIVAUDAN SA (CH) 2011-01-13 WO claimed
US-20260114489-A1 DRY PARTICLE COATING TO PRODUCE STABLE POWDERS GIVAUDAN SA (CH) 2026-04-30 US disclosed
EP-3911172-B1 COMBINATION OF SATIETY COMPONENTS WITH ARGININE SYMRISE AG (DE) 2026-04-15 EP disclosed
US-20260033524-A1 FLAVOR MODIFYING COMPOSITIONS CORN PRODUCTS DEV INC (US) 2026-02-05 US disclosed
EP-2451781-A1 PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR Givaudan SA (CH) 2012-05-16 EP disclosed
WO-2012035032-A2 TASTE ENHANCEMENT GIVAUDAN SA (CH) 2012-03-22 WO disclosed
WO-2011004016-A1 PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR GIVAUDAN SA (CH) 2011-01-13 WO disclosed
WO-2011004016-A1 PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR GIVAUDAN SA (CH) 2011-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260033524-A1 FLAVOR MODIFYING COMPOSITIONS TAS2R42, TAS2R7, TAS2R31 MAPT 973/4885KDM4E 4248/4885NPC1 2867/4885
US-20120121783-A1 Pyridine Derivatives With Umami Flavour C5, CHRM1, C9 MAPT 2520/4885KDM4E 414/4885NPC1 4083/4885
US-20140295045-A1 Pyridine Derivatives With Umami Flavour C5, CHRM1, C9 MAPT 2572/4885KDM4E 505/4885NPC1 4022/4885
US-20260114489-A1 DRY PARTICLE COATING TO PRODUCE STABLE POWDERS LIPA, DAGLA, SCD MAPT 1304/4885KDM4E 765/4885NPC1 268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.