Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.43 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30777576 | 1.00 | MAPT (0.56) | MAPTKDM4ESLC16A3SLC16A1LMNA | |
| SCHEMBL3704809 | 0.87 | KDM4E (0.59) | MAPTKDM4EMAOBRAB9ACYP1A2 | |
| SCHEMBL787766 | 0.87 | MAPT (0.61) | MAPTKDM4ELMNARAB9ACYP1A2 | |
| SCHEMBL30134679 | 0.87 | MAPT (0.61) | MAPTKDM4ELMNARAB9ACYP1A2 | |
| SCHEMBL793083 | 0.83 | KDM4E (0.55) | MAPTKDM4EMAOB | |
| SCHEMBL3703417 | 0.81 | KDM4E (0.53) | MAPTKDM4ELMNARAB9ACYP1A2 | |
| SCHEMBL4568616 | 0.81 | KDM4E (0.52) | MAPTKDM4EMAOBCYP1A2ALDH1A1 | |
| SCHEMBL933781 | 0.79 | KDM4E (0.51) | MAPTKDM4ELMNARAB9ACYP1A2 | |
| SCHEMBL3698715 | 0.78 | KDM4E (0.51) | MAPTKDM4ERAB9AALDH1A1NPC1 | |
| SCHEMBL933437 | 0.78 | KDM4E (0.42) | MAPTKDM4ESLC16A3SLC16A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2742983-B1 | Method for isolating fragrance and flavour compounds | SYMRISE AG (DE) | 2017-08-23 | — | — | EP | claimed |
| US-9173424-B2 | Pyridine derivatives with umami flavour | GIVAUDAN S.A. (CH) | 2015-11-03 | — | — | US | claimed |
| US-9144248-B2 | Cinnamamides as savory flavorings | SYMRISE AG (DE) | 2015-09-29 | — | — | US | claimed |
| US-20140295045-A1 | Pyridine Derivatives With Umami Flavour | GIVAUDAN S.A. (CH) | 2014-10-02 | — | — | US | claimed |
| EP-2742983-A1 | Method for isolating fragrance and flavour compounds | Symrise AG (DE) | 2014-06-18 | — | — | EP | claimed |
| EP-2451781-B1 | PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR | GIVAUDAN SA (CH) | 2013-09-18 | — | — | EP | claimed |
| EP-2529632-B1 | Cinnamic acid amides as spicy flavour agents | SYMRISE AG (DE) | 2013-08-28 | — | — | EP | claimed |
| US-20120308703-A1 | Cinnamamides as savory flavorings | SYMRISE AG (DE) | 2012-12-06 | — | — | US | claimed |
| EP-2529632-A1 | Cinnamic acid amides as spicy flavour agents | Symrise AG (DE) | 2012-12-05 | — | — | EP | claimed |
| US-20120121783-A1 | Pyridine Derivatives With Umami Flavour | GIVAUDAN SA (CH) | 2012-05-17 | — | — | US | claimed |
| EP-2451781-A1 | PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR | Givaudan SA (CH) | 2012-05-16 | — | — | EP | claimed |
| WO-2011004016-A1 | PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR | GIVAUDAN SA (CH) | 2011-01-13 | — | — | WO | claimed |
| EP-3911172-B1 | COMBINATION OF SATIETY COMPONENTS WITH ARGININE | SYMRISE AG (DE) | 2026-04-15 | — | — | EP | disclosed |
| US-20260014103-A1 | COMBINATION REMEDY | SYMRISE AG (DE) | 2026-01-15 | — | — | US | disclosed |
| EP-3823455-B1 | COMPOSITION FOR SUBSTITUTING SUGAR IN BAKED GOODS | SYMRISE AG (DE) | 2025-10-01 | — | — | EP | disclosed |
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
| WO-2012035032-A2 | TASTE ENHANCEMENT | GIVAUDAN SA (CH) | 2012-03-22 | — | — | WO | disclosed |
| WO-2011039340-A2 | FLAVOUR ENHANCEMENT | GIVAUDAN SA (CH) | 2011-04-07 | — | — | WO | disclosed |
| WO-2011004016-A1 | PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR | GIVAUDAN SA (CH) | 2011-01-13 | — | — | WO | disclosed |
| WO-2011004016-A1 | PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR | GIVAUDAN SA (CH) | 2011-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | MAPT 4340/4885KDM4E 3699/4885SLC16A3 1241/4885 |
| US-20120121783-A1 | Pyridine Derivatives With Umami Flavour | C5, CHRM1, C9 | MAPT 2520/4885KDM4E 414/4885SLC16A3 1785/4885 |
| US-20140295045-A1 | Pyridine Derivatives With Umami Flavour | C5, CHRM1, C9 | MAPT 2572/4885KDM4E 505/4885SLC16A3 1335/4885 |
| US-20260014103-A1 | COMBINATION REMEDY | TAS2R43, TAS2R41, TAS2R60 | MAPT 3252/4885KDM4E 3646/4885SLC16A3 4003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.