SCHEMBL793085

SCHEMBL793085

O=C1NC(=O)c2c(CO)cccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.47
ALDH1A1 P00352 3/20 0.47
GAA P10253 2/20 0.47
HPGD P15428 1/20 0.47
HSD17B10 Q99714 1/20 0.47
GSK3B P49841 2/20 0.46
PARP1 P09874 4/20 0.44
CHEK1 O14757 1/20 0.43
WEE1 P30291 1/20 0.43
PDK2 Q15119 1/20 0.42
CASP3 P42574 6/20 0.41
GSK3A P49840 1/20 0.41
CDK5 Q00535 1/20 0.41
CDK5R1 Q15078 1/20 0.41
CASP7 P55210 2/20 0.41
CASP2 P42575 1/20 0.41
CASP6 P55212 1/20 0.41
CASP8 Q14790 1/20 0.41
MEN1 O00255 2/20 0.41
POLB P06746 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1424202 0.85 KDM4E (0.45) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL5970012 0.84 GSK3B (0.50) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL10713059 0.84 GSK3B (0.50) KDM4EALDH1A1GAAHPGDHSD17B10
Water SCHEMBL10733874 0.84 KDM4E (0.44) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL2408327 0.82 KDM4E (0.49) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL6598413 0.82 KDM4E (0.43) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL7403092 0.81 KDM4E (0.42) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL1014384 0.81 GSK3B (0.46) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL113006 0.81 GSK3B (0.46) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL2744968 0.81 GSK3B (0.46) KDM4EALDH1A1GAAHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119143767-A Phthalimide phthalocyanine derivative, preparation method thereof, pigment composition and application 山东凯瑞尔光电科技有限公司 2024-12-17 CN claimed
CN-119059959-A Method for preparing N-chloromethyl phthalimide with low unit consumption 山东汇海医药化工有限公司 2024-12-03 CN claimed
EP-4347555-A1 METHOD FOR SYNTHESIZING 9-AMINOMETHYL TETRACYCLINE COMPOUNDS Hovione Scientia Limited (IE) 2024-04-10 EP claimed
CN-113501777-B Synthetic method of indoline-5-ylmethylamine dihydrochloride 上海毕得医药科技股份有限公司 2022-06-24 CN claimed
CN-107189010-B A kind of preparation method of hydrophobically modified polyacrylamide 山东大学 2019-04-12 CN claimed
CN-109111588-A The preparation method of resistance combustion polyurethane foam thermal insulation material 段瑶瑶 2019-01-01 CN claimed
CN-107189010-A A kind of preparation method of hydrophobically modified polyacrylamide 山东大学 2017-09-22 CN claimed
CN-105732889-B A kind of photoresist and its synthetic method 深圳市容大感光科技股份有限公司 2017-09-15 CN claimed
CN-104231141-B A kind of amino nitrogen heterocyclic ring resin and preparation method thereof 西安蓝晓科技新材料股份有限公司 2017-03-29 CN claimed
EP-0309861-B1 PROCESS FOR THE MANUFACTURE OF SYNTHETIC RESINS HAVING ANIONIC EXCHANGE PROPERTIES BAYER AG (DE) 1992-01-29 EP claimed
EP-0180812-B1 3,6 BIS(SUBSTITUTED) ACRIDINE DERIVATIVES AMERICAN CYANAMID COMPANY (US) 1991-05-15 EP claimed
EP-0309861-A2 Process for the manufacture of synthetic resins having anionic exchange properties BAYER AG (DE) 1989-04-05 EP claimed
EP-0180812-A2 3,6 Bis(substituted) acridine derivatives AMERICAN CYANAMID COMPANY (US) 1986-05-14 EP claimed
JP-2187469-A None JP disclosed
JP-7331182-A None JP disclosed
JP-1144412-A None JP disclosed
US-4370486-A Biphenyl compounds, a process for their preparation and their use as intermediate products for optical brighteners, dyestuffs, plastics and medicaments BAYER AKTIENGESELLSCHAFT (DE) 1983-01-25 US disclosed
EP-0047877-A2 Biphenyl compounds and process for their preparation BAYER AG (DE) 1982-03-24 EP disclosed
US-4144072-A CONTAINING A PHTHALAZINONE AND A PHTHALIMIDE FUJI PHOTO FILM CO., LTD. (JP) 1979-03-13 US disclosed
US-4008222-A POLYESTERS BAYER AKTIENGESELLSCHAFT (DT) 1977-02-15 US disclosed