SCHEMBL2408327

SCHEMBL2408327

CCc1cccc2c1C(=O)NC2=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 3/20 0.49
GAA P10253 1/20 0.49
HPGD P15428 1/20 0.49
HSD17B10 Q99714 1/20 0.49
GSK3B P49841 3/20 0.48
PARP1 P09874 4/20 0.45
CASP3 P42574 2/20 0.42
PDK2 Q15119 2/20 0.42
CDK4 P11802 1/20 0.42
CCND1 P24385 1/20 0.42
CASP7 P55210 2/20 0.42
CASP2 P42575 1/20 0.42
CASP6 P55212 1/20 0.42
CASP8 Q14790 1/20 0.42
CHEK1 O14757 1/20 0.41
WEE1 P30291 1/20 0.41
CYP2D6 P10635 1/20 0.41
GABRA1 P14867 2/20 0.40
GABRB2 P47870 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24673381 0.89 CASP3 (0.51) KDM4EALDH1A1GAAHPGDHSD17B10
Vinyl Chloride SCHEMBL28309108 0.88 KDM4E (0.41) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL1892075 0.87 KDM4E (0.45) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL8194264 0.86 KDM4E (0.42) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL5970012 0.86 GSK3B (0.50) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL10713059 0.86 GSK3B (0.50) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL166776 0.84 ELANE (0.43) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL29699198 0.84 ELANE (0.43) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL9980565 0.84 KDM4E (0.43) KDM4EALDH1A1GAAHPGDHSD17B10
Dodecylamine SCHEMBL27941935 0.83 ALDH1A1 (0.38) KDM4EALDH1A1GAAHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3669390-A1 REDOX FLOW BATTERIES AND COMPOUNDS FOR BATTERY APPLICATION The Trustees of Columbia University in the City of New York (US) 2020-06-24 EP claimed
CN-110306346-A A kind of refining dye enzyme and preparation method thereof promoting the anti-fuzz balls performance of cotton knitwear 广东湛丰精细化工有限公司 2019-10-08 CN claimed
CN-108558735-A A kind of synthetic method of commercial auxiliaries N- ethyl phthalimides 仪征市海帆化工有限公司 2018-09-21 CN claimed
CN-102503955-A Phthalimide nitrogen heteroaryl amide heteroaryl 15-crown ether and synthesis method thereof UNIV HARBIN NORMAL 2012-06-20 CN claimed
EP-2137220-A1 AROMATIC URETHANE ACRYLATES HAVING A HIGH REFRACTIVE INDEX Bayer MaterialScience AG (DE) 2009-12-30 EP claimed
WO-2009128088-A2 PREPARATION OF 2-(2-ALKOXY PHENOXY) ETHYLAMINE, AN INTERMEDIATE OF CARVEDILOL AND TAMSULOSIN SHODHANA LABORATORIES LIMITED (IN) 2009-10-22 WO claimed
CN-100519512-C Prepn process of 2-[2-(2,2,2-trifluoro ethoxy)] phenoxy ethamine UNIV CHINA PHARMA (CN) 2009-07-29 CN claimed
WO-2008125199-A1 AROMATIC URETHANE ACRYLATES HAVING A HIGH REFRACTIVE INDEX BAYER MATERIALSCIENCE AG (DE) 2008-10-23 WO claimed
EP-3459980-B1 FLUORINE-CONTAINING COPOLYMER DAIKIN IND LTD (JP) 2024-06-19 EP disclosed
WO-2023190309-A1 SURFACE-MODIFIER RESIN COMPOSITION 住友ベークライト株式会社 2023-10-05 WO disclosed
WO-2023125944-A1 COMPOUND CONTAINING HETEROCYCLIC RING 正大天晴药业集团股份有限公司 2023-07-06 WO disclosed
US-20230151236-A1 MAGENTA PIGMENT DISPERSANTS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2023-05-18 US disclosed
EP-4100473-A1 MAGENTA PIGMENT DISPERSANTS Hewlett-Packard Development Company, L.P. (US) 2022-12-14 EP disclosed
WO-2021257074-A1 MAGENTA PIGMENT DISPERSANTS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2021-12-23 WO disclosed
CN-1203247-A Akoxyl cross-link RTV1 silicon rubber mixture HUELS SILICONE GMBH (DE) 1998-12-30 CN disclosed
CN-1202506-A Alkoxy crosslinked RTV1 silastic mixture HUELS SILICONE GMBH (DE) 1998-12-23 CN disclosed
US-5811430-A 1 (2-pyrimidinyloxy) alkyl!-4- (heteroaryl) Piperidines and related compounds and their therapeutic utility HOECHST MARION ROUSSEL, INC. 1998-09-22 US disclosed
CN-1136275-A Arylheterocyclylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analgesics HOECHST ROUSSEL PHARMA (US) 1996-11-20 CN disclosed
CN-1111622-A Propenoic acid derivaties EISAI CO LTD (JP) 1995-11-15 CN disclosed
WO-1992001009-A1 COMPOSITION CONTAINING ALKANOLAMINES AND POLYISOCYANATES DSM N.V. (NL) 1992-01-23 WO disclosed