SCHEMBL2744968

SCHEMBL2744968

O=C1NC(=O)c2c(CCl)cccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 2/20 0.46
PARP1 P09874 5/20 0.44
KDM4E B2RXH2 4/20 0.44
ALDH1A1 P00352 3/20 0.44
GAA P10253 1/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CASP3 P42574 5/20 0.41
CASP7 P55210 2/20 0.41
CASP2 P42575 1/20 0.41
CASP6 P55212 1/20 0.41
CASP8 Q14790 1/20 0.41
GSK3A P49840 1/20 0.38
CDK5 Q00535 1/20 0.38
CDK5R1 Q15078 1/20 0.38
PPOX P50336 1/20 0.38
MEN1 O00255 2/20 0.37
POLB P06746 2/20 0.37
KMT2A Q03164 2/20 0.37
RGS12 O14924 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4515814 0.88 GSK3B (0.44) GSK3BPARP1KDM4EALDH1A1GAA
SCHEMBL10354541 0.85 GSK3B (0.43) GSK3BPARP1KDM4EALDH1A1GAA
SCHEMBL5970012 0.84 GSK3B (0.50) GSK3BPARP1KDM4EALDH1A1GAA
SCHEMBL10713059 0.84 GSK3B (0.50) GSK3BPARP1KDM4EALDH1A1GAA
SCHEMBL2359305 0.84 AURKA (0.34) GSK3BPARP1KDM4EALDH1A1GAA
SCHEMBL2408327 0.82 KDM4E (0.49) GSK3BPARP1KDM4EALDH1A1GAA
SCHEMBL5312970 0.82 GSK3B (0.41) GSK3BPARP1KDM4EALDH1A1GAA
SCHEMBL8969034 0.81 PARP1 (0.42) GSK3BPARP1KDM4EALDH1A1GAA
SCHEMBL1014384 0.81 GSK3B (0.46) GSK3BPARP1KDM4EALDH1A1GAA
SCHEMBL113006 0.81 GSK3B (0.46) GSK3BPARP1KDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110270133-A A kind of integral post plate preparation method and application based on PE sieve plate conjugation chemistry group 深圳市百迈生命科学有限公司 2019-09-24 CN claimed
CN-119528791-A Method for recovering N-hydroxymethyl phthalimide from 4-AA key intermediate residues 山东汇海医药化工有限公司 2025-02-28 CN disclosed
CN-110270133-A A kind of integral post plate preparation method and application based on PE sieve plate conjugation chemistry group 深圳市百迈生命科学有限公司 2019-09-24 CN disclosed
CN-110270133-A A kind of integral post plate preparation method and application based on PE sieve plate conjugation chemistry group 深圳市百迈生命科学有限公司 2019-09-24 CN disclosed
CN-110128843-A Fluorescent dye and its preparation method and application 深圳大学 2019-08-16 CN disclosed
CN-107108552-A Heterocyclic kinase inhibitors 百时美施贵宝公司 2017-08-29 CN disclosed
WO-2015108835-A1 3,3-DISUBSTITUTED-1-HYDROXYTRIAZ-1-ENE 2-OXIDES AND WOUND-HEALING COMPOSITIONS USING THEM SARMONT LLC (US) 2015-07-23 WO disclosed
US-20140371316-A1 DERIVATIVES OF PHENOXYISOBUTYRIC ACID FABRICANT JILL S (US) 2014-12-18 US disclosed
US-8859781-B2 No-releasing nonoate(nitrogen-bound)sulfonamide-linked-coxib anti-cancer agents Euclises Pharmaceuticals, Inc. (US) 2014-10-14 US disclosed
EP-2782902-A2 DERIVATIVES OF PHENOXYISOBUTYRIC ACID Fabricant, Jill, S. (US) 2014-10-01 EP disclosed
EP-0492442-A1 Photographic elements containing removable filter dye EASTMAN KODAK COMPANY (US) 1992-07-01 EP disclosed
US-5008288-A Skeletal & heat muscle disorders CEPTOR CORPORATION 1991-04-16 US disclosed
US-4866040-A DRUG COVALENTLY BONDED TO AMINOCARNITINE FOR DELIVERY TO SPECI FIC SITES CEPTOR CORPORATION 1989-09-12 US disclosed
US-4774265-A Process for preparing magnetic polymer particles SINTEF (NO) 1988-09-27 US disclosed
EP-0226346-A1 Bicyclic sulfonamide derivatives SHIONOGI & CO., LTD. (JP) 1987-06-24 EP disclosed
US-4654267-A Magnetic polymer particles and process for the preparation thereof SINTEF (NO) 1987-03-31 US disclosed
EP-0106873-B1 PROCESS FOR THE PRODUCTION OF MAGNETIC POLYMER PARTICLES SINTEF (NO) 1986-01-29 EP disclosed
WO-1984002031-A1 MAGNETIC POLYMER PARTICLES AND PROCESS FOR THE PREPARATION THEREOF SINTEF (NO) 1984-05-24 WO disclosed
EP-0106873-A1 PROCESS FOR THE PRODUCTION OF MAGNETIC POLYMER PARTICLES. SINTEF (NO) 1984-05-02 EP disclosed
WO-1983003920-A1 MAGNETIC POLYMER PARTICLES AND PROCESS FOR THE PREPARATION THEREOF SINTEF (NO) 1983-11-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140371316-A1 DERIVATIVES OF PHENOXYISOBUTYRIC ACID AGER, BPGM, FOSB GSK3B 201/4885PARP1 1215/4885KDM4E 244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.