SCHEMBL7930927

SCHEMBL7930927

Ic1cccc2c1C(I)c1ccccc1-2

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.34
HTR2A P28223 1/20 0.34
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
HDAC9 Q9UKV0 1/20 0.31
HDAC5 Q9UQL6 1/20 0.31
NCOR2 Q9Y618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18456445 0.78 KDM4E (0.39) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL5497775 0.78 GPR3 (0.33) GPR3HTR2A
SCHEMBL18243404 0.78 PPIA (0.33) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL7930812 0.77 GPR3 (0.46) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL20829599 0.74 GPR3 (0.44) GPR3HTR2AHDAC3HDAC4HDAC7
SCHEMBL18456626 0.73 GPR3 (0.62) GPR3HTR2A
SCHEMBL2229354 0.72 HTR2A (0.36) GPR3HTR2A
SCHEMBL8070100 0.71 GPR3 (0.40) GPR3
SCHEMBL16723344 0.69 MEN1 (0.46) HTR2A
SCHEMBL21311887 0.69 MEN1 (0.50) NCOR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227314-A1 CARBON NANOSTRUCTURE COMPOSITIONS AND METHODS FOR PURIFICATION THEREOF NANO-C, INC. 2023-07-20 US disclosed
WO-2021231365-A1 CARBON NANOSTRUCTURE COMPOSITIONS AND METHODS FOR PURIFICATION THEREOF NANO-C, INC. (US) 2021-11-18 WO disclosed
CN-107636216-B Isolated semiconductor single-walled nanotubes or metallic single-walled nanotubes and methods thereof 小利兰·斯坦福大学托管委员会 2021-08-24 CN disclosed
US-10395804-B2 Isolating semiconducting single-walled nanotubes or metallic single-walled nanotubes and approaches therefor THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2019-08-27 US disclosed
US-20160280548-A1 ISOLATING SEMICONDUCTING SINGLE-WALLED NANOTUBES OR METALLIC SINGLE-WALLED NANOTUBES AND APPROACHES THEREFOR THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2016-09-29 US disclosed
EP-0666267-B1 Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM CO (US) 2001-04-18 EP disclosed
EP-0574370-B1 Metallocene catalyst component with good catalyst efficiency after aging FINA TECHNOLOGY (US) 1998-03-11 EP disclosed
US-5571880-A CATALYSTS FOR POLYMERIZATION OF OLEFINS ESPECIALLY TO OBTAIN SYNDIOTACTIC POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1996-11-05 US disclosed
US-5449651-A Metallocene compound for a catalyst component with good catalyst efficiency after aging FINA TECHNOLOGY, INC. (US) 1995-09-12 US disclosed
EP-0666267-A2 Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1995-08-09 EP disclosed
US-5308817-A Containing polymerizable functional group, syndiotactic polymers, olefin polymerization FINA TECHNOLOGY, INC. (US) 1994-05-03 US disclosed
EP-0574370-A1 Metallocene catalyst component with good catalyst efficiency after aging FINA TECHNOLOGY, INC. (US) 1993-12-15 EP disclosed
US-4853308-A Photoresponsive imaging members with fluorene hole transporting layers XEROX CORPORATION (US) 1989-08-01 US disclosed
US-3980713-A FLUORESCENT BRIGHTENERS NIPPON KAYAKU CO., LTD. (JA) 1976-09-14 US disclosed