SCHEMBL8070100

SCHEMBL8070100

Ic1cccc2c1C(N(c1ccccc1)c1ccccc1)c1ccccc1-2

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.40
SLC22A2 O15244 1/20 0.33
SLC22A3 O75751 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1478412 0.80 GPR3 (0.54) GPR3SLC22A2SLC22A3
SCHEMBL18456626 0.79 GPR3 (0.62) GPR3SLC22A2SLC22A3
SCHEMBL9811554 0.79 GPR3 (0.39) GPR3SLC22A2SLC22A3
SCHEMBL7930927 0.71 GPR3 (0.34) GPR3
SCHEMBL18243404 0.69 PPIA (0.33) GPR3
SCHEMBL5497775 0.69 GPR3 (0.33) GPR3
SCHEMBL18456445 0.69 KDM4E (0.39) GPR3
SCHEMBL9811591 0.69 CYP1A2 (0.31) GPR3
SCHEMBL9811560 0.69 GPR3 (0.34) GPR3
SCHEMBL1477132 0.68 GPR3 (0.54) GPR3SLC22A2SLC22A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6100405-A Benzothiazole-containing two-photon chromophores exhibiting strong frequency upconversion THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2000-08-08 US disclosed