SCHEMBL7931041

SCHEMBL7931041

CC(Cc1cccc(CC(C)OOC(=O)C(=O)Cl)c1)OOC(=O)C(=O)Cl

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.40
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
GLRA1 P23415 1/20 0.37
PNMT P11086 1/20 0.37
TSHR P16473 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
NOS3 P29474 1/20 0.35
NOS1 P29475 1/20 0.35
NOS2 P35228 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TAAR1 Q96RJ0 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7921595 0.87 PTGS1 (0.40) TSHRNPC1RAB9A
SCHEMBL6348663 0.74 TAAR1 (0.42) SLC7A5PNMTTAAR1
SCHEMBL9134238 0.71 SLC7A5 (0.49) SLC7A5TSHRNPC1RAB9ANOS3
SCHEMBL2969179 0.70 TAAR1 (0.45) SLC7A5PNMTTAAR1
SCHEMBL8257100 0.69 TBXAS1 (0.53) SLC7A5TSHRNOS3NOS1NOS2
SCHEMBL8675590 0.68 TAAR1 (0.40) SLC7A5PNMTTAAR1
SCHEMBL44955 0.68 TAAR1 (0.50) SLC7A5PNMTTAAR1
SCHEMBL10920074 0.67 SLC7A5 (0.44) SLC7A5PNMTTSHR
SCHEMBL346630 0.66 SLC7A5 (0.46) SLC7A5PNMTNOS3NOS1NOS2
SCHEMBL7790688 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0850929-B1 Novel bis(mono- and diperoxy-oxalates) derived from dihydroperoxides and alkyl and alkylperoxy halooxalates ATOFINA CHEM INC (US) 2001-06-27 EP disclosed
US-5837782-A POLYMERIZATION CATALYST ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-11-17 US disclosed
EP-0850929-A1 Novel bis(mono- and diperoxy-oxalates) derived from dihydroperoxides and alkyl and alkylperoxy halooxalates ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-07-01 EP disclosed