SCHEMBL44955

SCHEMBL44955

COC(C)Cc1cccc(CC(C)OC)c1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.50
SLC6A2 P23975 2/20 0.46
MAOA P21397 1/20 0.46
SLC6A4 P31645 1/20 0.46
SLC6A3 Q01959 1/20 0.46
SIGMAR1 Q99720 1/20 0.46
CYP2A6 P11509 1/20 0.46
ADORA2A P29274 1/20 0.46
ADORA1 P30542 1/20 0.46
PNMT P11086 1/20 0.44
SLC7A5 Q01650 2/20 0.44
HTR2A P28223 1/20 0.40
HTR2C P28335 1/20 0.40
HTR2B P41595 1/20 0.40
SLC18A2 Q05940 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16213676 0.90 TAAR1 (0.43) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL15333594 0.86 TAAR1 (0.43) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL13189946 0.86 SIGMAR1 (0.56) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL2555409 0.86 SIGMAR1 (0.56) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL13006663 0.86 SIGMAR1 (0.56) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL45193 0.85 TAAR1 (0.33) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL16014057 0.83 HTR2A (0.47) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL25480447 0.80 MAOB (0.63) TAAR1MAOA
SCHEMBL43314 0.80 SLC6A4 (0.46) TAAR1SLC6A2MAOASLC6A4SLC6A3
SCHEMBL2969179 0.80 TAAR1 (0.45) TAAR1SLC6A2MAOASLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8063154-B2 Preparation of exo-olefin terminated polyolefins via quenching with alkoxysilanes or ethers THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2011-11-22 US claimed
US-8013073-B2 Method for preparing polyolefins containing vinylidine end groups using nonaromatic heterocyclic compounds CHEVRON ORONITE COMPANY LLC (US) 2011-09-06 US claimed
US-7816459-B2 Method for preparing polyolefins containing vinylidine end groups using polymeric nitrogen compounds CHEVRON ORONITE COMPANY LLC (US) 2010-10-19 US claimed
EP-1803751-B1 Method for preparing polyolefins containing vinylidene end groups using polymeric nitrogen compounds CHEVRON ORONITE CO (US) 2010-06-30 EP claimed
EP-1803748-B1 Method for preparing polyolefins containing vinylidene end groups using nonaromatic heterocyclic compounds CHEVRON ORONITE CO (US) 2010-06-09 EP claimed
US-20090318624-A1 Preparation of exo-olefin terminated polyolefins via quenching with alkoxysilanes or ethers UNIVERSITY OF SOUTHERN MISSISSIPPI 2009-12-24 US claimed
US-20090247716-A1 Production of Vinylidene-Terminated Polyolefins Via Quenching with Monosulfides CHEVRON ORONITE COMPANY LLC 2009-10-01 US claimed
EP-1803741-B1 Method for preparing polyolefins containing vinylidene groups using azole compounds CHEVRON ORONITE CO (US) 2009-01-21 EP claimed
US-20070155911-A1 Method for preparing polyolefins containing vinylidine end groups using nonaromatic heterocyclic compounds UNIVERSITY OF SOUTHERN MISSISSIPPI 2007-07-05 US claimed
US-20070155910-A1 Method for preparing polyolefins containing vinylidine end groups using polymeric nitrogen compounds CHEVRON ORONITE COMPANY LLC 2007-07-05 US claimed
US-20070155908-A1 contacting a olefin monomer (isobutylene) with an initiator( 2-chloro-2,4,4,-trimethylpentane) in the presence of a Lewis acid and solvent under suitable quasiliving polymerization reaction conditions, contacting quasiliving carbocationically terminated polymer with an oxazole or thiazoles quencher CHEVRON ORONITE COMPANY LLC 2007-07-05 US claimed
EP-1803748-A1 Method for preparing polyolefins containing vinylidene end groups using nonaromatic heterocyclic compounds Chevron Oronite Company LLC (US) 2007-07-04 EP claimed
EP-1803751-A1 Method for preparing polyolefins containing vinylidene end groups using polymeric nitrogen compounds Chevron Oronite Company LLC (US) 2007-07-04 EP claimed
EP-1803741-A1 Method for preparing polyolefins containing vinylidene groups using azole compounds Chevron Oronite Company LLC (US) 2007-07-04 EP claimed
US-11274181-B2 Polyimide dispersants and methods of making and using thereof CHEVRON ORONITE COMPANY LLC (US) 2022-03-15 US disclosed
EP-3684894-A1 POLYIMIDE DISPERSANTS AND METHODS OF MAKING AND USING THEREOF Chevron Oronite Company LLC (US) 2020-07-29 EP disclosed
EP-2291418-B1 PREPARATION OF EXO-OLEFIN TERMINATED POLYOLEFINS VIA QUENCHING WITH ALKOXYSILANES THE UNIV OF SOUTHERN MISSISSIPPI (US) 2020-06-17 EP disclosed
WO-2009129015-A1 COPOLYMERS MADE WITH QUASI-LIVING POLYOLEFINS AND UNSATURATED ACIDIC REAGENTS, DISPERSANTS USING SAME, AND METHODS OF MAKING SAME CHEVRON ORONITE COMPANY LLC (US) 2009-10-22 WO disclosed
US-20090258803-A1 COPOLYMERS MADE WITH QUASI-LIVING POLYOLEFINS AND UNSATURATED ACIDIC REAGENTS, DISPERSANTS USING SAME, AND METHODS OF MAKING SAME CHEVRON ORONITE COMPANY, LLC 2009-10-15 US disclosed
US-20090247716-A1 Production of Vinylidene-Terminated Polyolefins Via Quenching with Monosulfides CHEVRON ORONITE COMPANY LLC 2009-10-01 US disclosed