Biphenyl

Biphenyl

SCHEMBL7931070

O=C(NSSNC(=O)c1ccccc1)c1ccccc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.61
RAB9A P51151 2/20 0.61
CTDSP1 Q9GZU7 2/20 0.61
PTPN1 P18031 3/20 0.53
HDAC1 Q13547 3/20 0.52
HDAC2 Q92769 3/20 0.52
HDAC8 Q9BY41 2/20 0.52
HDAC3 O15379 2/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
IDO1 P14902 1/20 0.52
ALOX15 P16050 1/20 0.52
CA9 Q16790 1/20 0.52
HDAC7 Q8WUI4 1/20 0.52
HSD17B10 Q99714 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
NCOR2 Q9Y618 1/20 0.52
GAA P10253 1/20 0.48
HPGDS O60760 1/20 0.47
MEN1 O00255 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3946799 0.93 ALOX15 (0.58) NPC1RAB9ACTDSP1PTPN1HDAC1
SCHEMBL28343144 0.79 ALOX15 (0.58) NPC1RAB9ACTDSP1PTPN1HDAC1
Biphenyl SCHEMBL27419692 0.79 NPC1 (0.68) NPC1RAB9ACTDSP1PTPN1HDAC1
SCHEMBL27515367 0.77 ALOX15 (0.56) NPC1RAB9ACTDSP1PTPN1HDAC1
SCHEMBL7820075 0.76 HDAC3 (0.54) NPC1RAB9ACTDSP1HDAC1HDAC2
SCHEMBL20094759 0.76 CA12 (0.54) NPC1RAB9ACTDSP1PTPN1HDAC1
Water SCHEMBL28201280 0.74 HDAC3 (0.52) NPC1RAB9ACTDSP1HDAC1HDAC2
SCHEMBL9274738 0.74 ALOX15 (0.52) NPC1RAB9ACTDSP1PTPN1HDAC1
SCHEMBL27502838 0.74 NPC1 (0.53) NPC1RAB9ACTDSP1PTPN1HDAC1
SCHEMBL11570198 0.72 HDAC3 (0.50) NPC1RAB9ACTDSP1PTPN1HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107964134-A The environmentally friendly mining ageing-resistant low heat generation tire tread glue of all-steel engineering radial 风神轮胎股份有限公司 2018-04-27 CN claimed
CN-107083178-A A kind of antifriction polyurethane coating and preparation method thereof 段小宁 2017-08-22 CN claimed
WO-2000038794-A9 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AN ORGANOSULFUR CATALYST AND METHOD FOR MAKING SAME ACUSHNET CO (US) 2001-11-01 WO claimed
WO-2000038794-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AN ORGANOSULFUR CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO claimed
CN-109776367-A A kind of method of synthetic rubber peptizer 江苏华星新材料科技股份有限公司 2019-05-21 CN disclosed
CN-107964134-A The environmentally friendly mining ageing-resistant low heat generation tire tread glue of all-steel engineering radial 风神轮胎股份有限公司 2018-04-27 CN disclosed
CN-105579247-B Sulfur-crosslinkable rubber blend and vehicle tire 大陆轮胎德国有限公司 2017-09-29 CN disclosed
CN-105579504-B Sulfur-crosslinkable rubber mixtures 大陆轮胎德国有限公司 2017-09-22 CN disclosed
CN-105579507-B The crosslinkable rubber composition of sulphur 大陆轮胎德国有限公司 2017-09-08 CN disclosed
CN-107109067-A Sulfur-containing polyorganosiloxane compositions and related aspects 美国道康宁公司 2017-08-29 CN disclosed
CN-104672380-B Functionalized polymeric, rubber composition and pneumatic tire 固特异轮胎和橡胶公司 2017-08-25 CN disclosed
CN-107083178-A A kind of antifriction polyurethane coating and preparation method thereof 段小宁 2017-08-22 CN disclosed
CN-105358334-A Rubber mixture and vehicle tire CONTINENTAL REIFEN DEUTSCHLAND 2016-02-24 CN disclosed
CN-105358335-A Rubber mixture and pneumatic vehicle tyre CONTINENTAL REIFEN DEUTSCHLAND 2016-02-24 CN disclosed
CN-104736358-A Pneumatic tire YOKOHAMA RUBBER CO LTD 2015-06-24 CN disclosed
CN-102497999-B Vehicle tire CONTINENTAL REIFEN DEUTSCHLAND 2014-06-18 CN disclosed
CN-102497999-A Vehicle tire CONTINENTAL REIFEN DEUTSCHLAND 2012-06-13 CN disclosed
CN-101735363-A Grafted and functionalized high 1,4-trans polybutadiene with aromatic organosulfur compound KOREA KUMHO PETROCHEM CO LTD 2010-06-16 CN disclosed
US-6235363-B1 COMPOSITE FOR LABELS OR TAPE AVERY DENNISON CORPORATION 2001-05-22 US disclosed
US-5085905-A Polysulfide adhesion promoter DAYCO PRODUCTS, INC. (US) 1992-02-04 US disclosed