SCHEMBL28343144

SCHEMBL28343144

O=C(NSNC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.58
HDAC3 O15379 1/20 0.58
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
IDO1 P14902 1/20 0.58
HDAC1 Q13547 1/20 0.58
CA9 Q16790 1/20 0.58
HDAC7 Q8WUI4 1/20 0.58
HDAC2 Q92769 1/20 0.58
HSD17B10 Q99714 1/20 0.58
HDAC8 Q9BY41 1/20 0.58
HDAC6 Q9UBN7 1/20 0.58
NCOR2 Q9Y618 1/20 0.58
GAA P10253 1/20 0.54
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
CTDSP1 Q9GZU7 1/20 0.50
PTGS2 P35354 1/20 0.50
MAPT P10636 3/20 0.48
TDP1 Q9NUW8 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27272343 0.89 ALDH1A1 (0.50) ALOX15HDAC3CA12CA1IDO1
SCHEMBL3946799 0.85 ALOX15 (0.58) ALOX15HDAC3CA12CA1IDO1
SCHEMBL27515367 0.83 ALOX15 (0.56) ALOX15HDAC3CA12CA1IDO1
SCHEMBL7820075 0.81 HDAC3 (0.54) ALOX15HDAC3CA12CA1IDO1
SCHEMBL20094759 0.81 CA12 (0.54) ALOX15HDAC3CA12CA1IDO1
Pyridine SCHEMBL28224545 0.80 JAK2 (0.47) ALOX15HDAC3CA12CA1IDO1
SCHEMBL9131712 0.80 CYP1A2 (0.46) ALOX15HDAC3CA12CA1IDO1
Biphenyl SCHEMBL7931070 0.79 NPC1 (0.61) ALOX15HDAC3CA12CA1IDO1
SCHEMBL9274738 0.79 ALOX15 (0.52) ALOX15HDAC3CA12CA1IDO1
Water SCHEMBL28201280 0.79 HDAC3 (0.52) ALOX15HDAC3CA12CA1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110483438-A A kind of duct type continuous production method of 3- iso thiazoline ketone compound DALIAN BIO CHEM SHARE CO LTD 2019-11-22 CN disclosed
CN-107249580-A Parkin ligase activation methods and compositions AN2H探索有限公司 2017-10-13 CN disclosed