SCHEMBL7931246

SCHEMBL7931246

C=CCOC(=O)C(=C)C=CC(=O)O.C=CCOC(=O)C=C

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.40
CACNA1B Q00975 1/20 0.40
APBA1 Q02410 1/20 0.40
TSHR P16473 7/20 0.36
ALDH1A1 P00352 4/20 0.36
TP53 P04637 3/20 0.36
HIF1A Q16665 3/20 0.36
CYP3A4 P08684 3/20 0.36
HSD17B10 Q99714 1/20 0.36
HCAR2 Q8TDS4 8/20 0.35
APP P05067 1/20 0.34
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HPGD P15428 1/20 0.33
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL250194 0.91 MAPT (0.38) MAPTCACNA1BAPBA1TSHRALDH1A1
Maleic Acid SCHEMBL28759479 0.88 MAPT (0.48) MAPTCACNA1BAPBA1TSHRALDH1A1
Acrylamide SCHEMBL5176054 0.87 MAPT (0.40) MAPTCACNA1BAPBA1TSHRALDH1A1
1,1-Dichloroethene SCHEMBL7569931 0.86 MAPT (0.35) MAPTCACNA1BAPBA1TSHRALDH1A1
SCHEMBL2359268 0.84 MAPT (0.55) MAPTCACNA1BAPBA1TSHRALDH1A1
SCHEMBL2359270 0.84 MAPT (0.55) MAPTCACNA1BAPBA1TSHRALDH1A1
Methacrylic Acid SCHEMBL8516310 0.83 HCAR2 (0.35) MAPTCACNA1BAPBA1TSHRALDH1A1
SCHEMBL754655 0.81 MAPT (0.41) MAPTCACNA1BAPBA1TSHRALDH1A1
SCHEMBL2641210 0.80 TSHR (0.42) MAPTCACNA1BAPBA1TSHRALDH1A1
Acrylic Acid SCHEMBL170500 0.80 TSHR (0.48) MAPTCACNA1BAPBA1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6184264-B1 CAPABLE OF BEING SWITCHED FORM TACK TO NON-TACKY STATE; SUITED FOR MEDICAL DRESSINGS SMITH & NEPHEW PLC (GB) 2001-02-06 US claimed
EP-0863775-B1 ADHESIVES SMITH & NEPHEW (GB) 2000-10-18 EP claimed
EP-0863775-A2 ADHESIVES Smith & Nephew plc (GB) 1998-09-16 EP claimed
WO-1997006836-A2 ADHESIVES SMITH & NEPHEW PLC (GB) 1997-02-27 WO claimed
US-6184264-B1 CAPABLE OF BEING SWITCHED FORM TACK TO NON-TACKY STATE; SUITED FOR MEDICAL DRESSINGS SMITH & NEPHEW PLC (GB) 2001-02-06 US disclosed
EP-0863775-B1 ADHESIVES SMITH & NEPHEW (GB) 2000-10-18 EP disclosed
EP-0863775-A2 ADHESIVES Smith & Nephew plc (GB) 1998-09-16 EP disclosed
WO-1997006836-A2 ADHESIVES SMITH & NEPHEW PLC (GB) 1997-02-27 WO disclosed