Acrylic Acid

Acrylic Acid

SCHEMBL170500

C=CC(=O)O.C=CCOC(=O)C=C

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.48
ALDH1A1 P00352 5/20 0.48
TP53 P04637 3/20 0.48
HIF1A Q16665 3/20 0.48
CYP3A4 P08684 3/20 0.48
HSD17B10 Q99714 3/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.47
CACNA1B Q00975 1/20 0.47
APBA1 Q02410 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.43
MAPK1 P28482 1/20 0.43
HPGD P15428 1/20 0.43
THRB P10828 2/20 0.40
APP P05067 1/20 0.39
ALOX15 P16050 1/20 0.37
TDP1 Q9NUW8 1/20 0.35
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL28462478 1.00 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylic Acid SCHEMBL459309 0.98 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
Bicarbonate SCHEMBL1577827 0.93 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL5167665 0.93 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL31267242 0.93 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL19273 0.93
Acrylic Acid SCHEMBL1173511 0.92 MAPT (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylic Acid SCHEMBL20238760 0.92 MAPT (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
Maleic Acid SCHEMBL28759479 0.91 MAPT (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
Charcoal, Activated SCHEMBL3744730 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1282 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216258-A1 HAIR COSMETIC KAO CORPORATION (JP) 2024-07-04 US claimed
WO-2024134242-A1 OIL-IN-WATER EMULSION L V M H RECHERCHE (FR) 2024-06-27 WO claimed
CN-118055755-A Topical compositions for imparting active shine to skin 联合利华知识产权控股有限公司 2024-05-17 CN claimed
WO-2024088996-A1 AQUEOUS MAKE-UP-REMOVING COMPOSITION HAVING A MILD PEELING EFFECT L'OREAL (FR) 2024-05-02 WO claimed
CN-117715521-A Alcohol-based hand sanitizer compositions with improved feel 莎罗雅株式会社 2024-03-15 CN claimed
WO-2024048324-A1 POWDER DISPERSION COMPOSITION, AND COSMETIC 株式会社資生堂 2024-03-07 WO claimed
WO-2024046943-A1 USE OF A COMPOSITION FOR BOOSTING SKIN'S NIGHT REPAIR ASSOCIATED FUNCTIONS UNILEVER IP HOLDINGS B.V. (NL) 2024-03-07 WO claimed
EP-4331565-A1 HAIR COSMETIC Kao Corporation (JP) 2024-03-06 EP claimed
WO-2023057266-A1 A TOPICAL COMPOSITION FOR PROVIDING ENERGIZING GLOW ON SKIN UNILEVER IP HOLDINGS B.V. (NL) 2023-04-13 WO claimed
WO-2023047979-A1 OIL-IN-WATER EMULSIFIED COSMETIC MATERIAL 株式会社 資生堂 2023-03-30 WO claimed
US-20040138458-A1 Oxidation process for highly dispersible quinacridone pigments CIBA SPECIALTY CHEMICALS CORP. 2004-07-15 US claimed
US-20040013698-A1 Method for preparing topical preparations containing skin protective agents with enhanced barrier properties ENGELHARD CORPORATION 2004-01-22 US claimed
WO-2002003925-A1 METHOD FOR PREPARING TOPICAL PREPARATIONS CONTAINING SKIN PROTECTIVE AGENTS WITH ENHANCED BARRIER PROPERTIES COLLABORATIVE TECHNOLOGIES, INC. (US) 2002-01-17 WO claimed
WO-2001070271-A2 ACID-STABLE BASE COMPOSITIONS FOR PREPARING SURFACTANT FREE TOPICAL COMPOSITIONS COLLABORATIVE TECHNOLOGIES, INC. (US) 2001-09-27 WO claimed
WO-2001070270-A2 BASE COMPOSITIONS FOR PREPARING SURFACTANT FREE TOPICAL COMPOSITIONS COLLABORATIVE TECHNOLOGIES, INC. (US) 2001-09-27 WO claimed
US-5914102-A AQUEOUS PHASE, EMULSIFIER, OIL PHASE CONTAINING SUBMICRON SILICA PARTICLES HAVING A HYDROPHOBIC SURFACE AND AT LEAST ONE ACTIVE SUNSCREEN AGENT, THE CONCENTRATION RATIO OF SUNSCREEN AGENTS TO SILICA BEING AT LEAST ABOUT 30 SCHERING-PLOUGH HEALTHCARE PRODUCTS, INC. (US) 1999-06-22 US claimed
WO-1999026599-A1 HIGH SPF PERSPIRATION-RESISTANT SUNSCREEN SCHERING-PLOUGH HEALTHCARE PRODUCTS, INC. (US) 1999-06-03 WO claimed
EP-0919222-A1 High SPF perspiration-resistant sunscreen SCHERING-PLOUGH HEALTHCARE PRODUCTS, INC. (US) 1999-06-02 EP claimed
EP-0834301-A1 Compositions comprising glutathione liposomes Boehringer Ingelheim Limited (GB) 1998-04-08 EP claimed
US-5679324-A CONTAINING ETHOXYLATED AND/OR PROPOXYLATED LANOLIN OIL SURFACTANT, FLUOROCARBON AND/OR HYDROCARBON GAS PROPELLANT, FRAGRANCE, THICKENER, COSMETIC VEHICLE THE PROCTER & GAMBLE CO. (US) 1997-10-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216258-A1 HAIR COSMETIC DSG1, DSC1, POLR1C TSHR 3468/4885ALDH1A1 1340/4885TP53 208/4885
US-20040013698-A1 Method for preparing topical preparations containing skin protective agents with enhanced barrier properties CUTA, DSG1, TTPA TSHR 4823/4885ALDH1A1 2210/4885TP53 2148/4885
US-20040138458-A1 Oxidation process for highly dispersible quinacridone pigments NDUFA6, NDUFS6, NDUFA3 TSHR 4164/4885ALDH1A1 88/4885TP53 1574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.