SCHEMBL250194

SCHEMBL250194

C=CCOC(=O)C(=C)C=CC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.38
CACNA1B Q00975 1/20 0.38
APBA1 Q02410 1/20 0.38
HCAR2 Q8TDS4 6/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 4/20 0.36
TP53 P04637 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
EGLN3 Q9H6Z9 1/20 0.36
ALDH1A1 P00352 4/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPK1 P28482 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PKM P14618 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
APP P05067 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,1-Dichloroethene SCHEMBL7569931 0.94 MAPT (0.35) MAPTCACNA1BAPBA1HCAR2CYP3A4
Methacrylic Acid SCHEMBL8516310 0.91 HCAR2 (0.35) MAPTCACNA1BAPBA1HCAR2CYP3A4
SCHEMBL7931246 0.91 MAPT (0.40) MAPTCACNA1BAPBA1HCAR2CYP3A4
Acrylamide SCHEMBL5176054 0.91 MAPT (0.40) MAPTCACNA1BAPBA1HCAR2CYP3A4
SCHEMBL2641296 0.87 MAPT (0.31) MAPTCACNA1BAPBA1
Styrene SCHEMBL327472 0.84 CYP3A4 (0.44) MAPTHCAR2CYP3A4TSHRALDH1A1
Fumaric Acid SCHEMBL10815260 0.82 TSHR (0.42) MAPTCACNA1BAPBA1HCAR2CYP3A4
Fumaric Acid SCHEMBL10815254 0.82 TSHR (0.42) MAPTCACNA1BAPBA1HCAR2CYP3A4
Acrylic Acid SCHEMBL22228242 0.82 LMNA (0.34) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL5140990 0.79 CYP3A4 (0.41) MAPTCACNA1BAPBA1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11197874-B2 Use of an amphoteric chelating agent for preventing contact allergies PREVOR INTERNATIONAL (FR) 2021-12-14 US claimed
EP-2874604-B1 USE OF AN AMPHOTERIC CHELATING AGENT FOR PREVENTING CONTACT ALLERGIES PREVOR INT (FR) 2018-02-14 EP claimed
US-20150202217-A1 USE OF AN AMPHOTERIC CHELATING AGENT FOR PREVENTING CONTACT ALLERGIES PREVOR INTERNATIONAL (FR) 2015-07-23 US claimed
US-20150119510-A1 INKJET INK CONTAINING POLYSTYREN COPOLYMER LATEX SUITABLE FOR INDIRECT PRINTING XEROX CORPORATION (US) 2015-04-30 US claimed
EP-2655059-A1 WATER SOLUBLE PACKAGE FILMS FOR ACIDIC PRODUCT AND METHOD FOR ADDING ACIDIC PRODUCT TO WATER SYSTEM General Electric Company (US) 2013-10-30 EP claimed
US-20130256237-A1 WATER SOLUBLE PACKAGE FILMS FOR ACIDIC HIGH WATER CONTENT PRODUCT AND METHOD OF PRODUCING THE SAME GENERAL ELECTRIC COMPANY 2013-10-03 US claimed
WO-2012083478-A1 WATER SOLUBLE PACKAGE FILMS FOR ACIDIC PRODUCT AND METHOD FOR ADDING ACIDIC PRODUCT TO WATER SYSTEM GENERAL ELECTRIC COMPANY (US) 2012-06-28 WO claimed
JP-4791732-B2 2011-10-12 JP claimed
EP-1583803-B1 OXIDATION PROCESS FOR PREPARING HIGHLY DISPERSIBLE QUINACRIDONE PIGMENTS BASF SE (DE) 2010-07-28 EP claimed
US-7579128-B2 Toner compositions including styrene containing external additives XEROX CORPORATION (US) 2009-08-25 US claimed
EP-2067795-A1 A method for producing a functional vinyl halide polymer Formosa Plastics Corporation (TW) 2009-06-10 EP claimed
US-20090143547-A1 METHOD FOR PRODUCING A FUNCTIONAL VINYL HALIDE POLYMER FORMOSA PLASTICS CORPORATION (TW) 2009-06-04 US claimed
US-20080241724-A1 TONER COMPOSITIONS INCLUDING STYRENE CONTAINING EXTERNAL ADDITIVES XEROX CORPORATION (US) 2008-10-02 US claimed
EP-1721963-B1 Hard surface cleaning compositions and methods for making same INT FLAVORS & FRAGRANCES INC (US) 2008-02-20 EP claimed
US-20060258557-A1 Hard surface cleaning compositions and methods for making same INTERNATIONAL FLAVORS & FRAGRANCES INC. 2006-11-16 US claimed
EP-1721963-A1 Hard surface cleaning compositions and methods for making same INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) 2006-11-15 EP claimed
EP-1583803-A1 OXIDATION PROCESS FOR PREPARING HIGHLY DISPERSIBLE QUINACRIDONE PIGMENTS Ciba SC Holding AG (CH) 2005-10-12 EP claimed
US-6867301-B2 Oxidation process for highly dispersible quinacridone pigments CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-03-15 US claimed
WO-2004063284-A1 OXIDATION PROCESS FOR PREPARING HIGHLY DISPERSIBLE QUINACRIDONE PIGMENTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-07-29 WO claimed
US-20040138458-A1 Oxidation process for highly dispersible quinacridone pigments CIBA SPECIALTY CHEMICALS CORP. 2004-07-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040138458-A1 Oxidation process for highly dispersible quinacridone pigments NDUFA6, NDUFS6, NDUFA3 MAPT 893/4885CACNA1B 4611/4885APBA1 3815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.