Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7939937 | 0.84 | DNMT1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL6557718 | 0.84 | MEN1 (0.40) | MEN1POLBKMT2AATM | |
| Hydrochloric Acid SCHEMBL7940442 | 0.74 | DNMT1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL7930826 | 0.73 | MEN1 (0.31) | MEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL9165907 | 0.72 | MEN1 (0.33) | MEN1POLBKMT2AATM | |
| SCHEMBL8824255 | 0.71 | MEN1 (0.37) | MEN1POLBKMT2AATM | |
| Hydrochloric Acid SCHEMBL5081119 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL7931293 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL7939984 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL2863535 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123938-A2 | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 2001-08-16 | — | — | EP | disclosed |