Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27566040 | 0.94 | LMNA (0.50) | KDM4EAKR1C1KMT2ALMNAMAPT | |
| SCHEMBL4194919 | 0.91 | LMNA (0.56) | KDM4EAKR1C1KMT2ALMNAMAPT | |
| SCHEMBL27915223 | 0.91 | LMNA (0.56) | KDM4EAKR1C1KMT2ALMNAMAPT | |
| SCHEMBL27826008 | 0.90 | LMNA (0.46) | KDM4EAKR1C1KMT2ALMNAMAPT | |
| SCHEMBL28085775 | 0.86 | TSHR (0.51) | KDM4EKMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL27915219 | 0.86 | ALDH1A1 (0.58) | KDM4EKMT2ALMNAMAPTMEN1 | |
| SCHEMBL15673155 | 0.84 | KMT2A (0.70) | KDM4EKMT2ALMNAMAPTL3MBTL1 | |
| SCHEMBL24704034 | 0.84 | MEN1 (0.70) | KDM4EAKR1C1KMT2ALMNAMAPT | |
| SCHEMBL7527305 | 0.84 | MEN1 (0.70) | KDM4EAKR1C1KMT2ALMNAMAPT | |
| SCHEMBL648889 | 0.84 | MEN1 (0.70) | KDM4EAKR1C1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331502-B1 | PALLADIUM COMPOUND, ORGANOPHOSPHORUS LIGAND, ACID PROMOTER, PROTON SOURCE; AND HYDROXY- OR CARBOXY-SUBSTITUTED PYRIDINE, PIPERIDINE, QUINOLINE OR ISOQUINOLINE COMPOUND; OXIDATION, ESTERIFICATION; CARBONYLATION OF ALKYNES CATALYSIS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2001-12-18 | — | — | US | disclosed |