Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | QRFPR | Q96P65 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26112729 | 0.76 | QRFPR (0.43) | ESR1ESR2QRFPROPRD1 | |
| SCHEMBL8511938 | 0.75 | BACE1 (0.34) | ESR1ESR2IDO1TDO2QRFPR | |
| SCHEMBL8586278 | 0.73 | MAPT (0.50) | ESR1ESR2IDO1TDO2 | |
| SCHEMBL8355981 | 0.73 | ESR1 (0.39) | ESR1ESR2IDO1TDO2 | |
| SCHEMBL986215 | 0.71 | ESR2 (0.68) | ESR1ESR2 | |
| SCHEMBL7927948 | 0.71 | PTGDR2 (0.39) | ESR1ESR2TTR | |
| SCHEMBL4668221 | 0.70 | ESR1 (0.50) | ESR1ESR2IDO1TDO2 | |
| SCHEMBL15717660 | 0.70 | ESR2 (0.71) | ESR1ESR2 | |
| Ammonia Solution, Strong SCHEMBL4910431 | 0.69 | ESR1 (0.48) | ESR1ESR2IDO1TDO2 | |
| SCHEMBL18076562 | 0.68 | BACE1 (0.46) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235871-B1 | Synthesis of oligoarylamines, and uses and reagents related thereto | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2001-05-22 | — | — | US | disclosed |
| WO-1999028290-A1 | SYNTHESIS OF OLIGOARYLAMINES, AND USES AND REAGENTS RELATED THERETO | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1999-06-10 | — | — | WO | disclosed |