Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 6/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6135928 | 0.79 | ESR1 (0.44) | ESR1ESR2HTR3EHTR3BHTR3A | |
| SCHEMBL30402030 | 0.78 | ESR1 (0.40) | ESR1ESR2HTR3EHTR3BHTR3A | |
| SCHEMBL24399684 | 0.75 | CYP3A4 (0.44) | ESR1ESR2HTR3EHTR3BHTR3A | |
| SCHEMBL7931343 | 0.73 | ESR1 (0.40) | ESR1ESR2IDO1TDO2 | |
| SCHEMBL29220712 | 0.73 | HTR3E (0.55) | LMNAESR1ESR2HTR3EHTR3B | |
| SCHEMBL30886807 | 0.73 | ESR1 (0.38) | MAPTMEN1KMT2ALMNAEPHX1 | |
| SCHEMBL11735726 | 0.72 | MEN1 (0.61) | MAPTMEN1KMT2ALMNAEPHX1 | |
| SCHEMBL8355981 | 0.72 | ESR1 (0.39) | ESR1ESR2IDO1TDO2 | |
| SCHEMBL11822345 | 0.71 | HTR3E (0.42) | MAPTMEN1KMT2ALMNAEPHX1 | |
| SCHEMBL11822338 | 0.71 | HTR3E (0.42) | MAPTMEN1KMT2ALMNAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028290-A1 | SYNTHESIS OF OLIGOARYLAMINES, AND USES AND REAGENTS RELATED THERETO | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1999-06-10 | — | — | WO | disclosed |