Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.48 |
| ▸ | IDO1 | P14902 | 6/20 | 0.43 |
| ▸ | TDO2 | P48775 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | C1S | P09871 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668221 | 0.98 | ESR1 (0.50) | ESR1ESR2IDO1TDO2HPGD | |
| SCHEMBL4450591 | 0.77 | ESR2 (0.74) | ESR1ESR2MEN1LMNAKMT2A | |
| SCHEMBL5249715 | 0.77 | ESR2 (0.62) | ESR1ESR2MEN1LMNAKMT2A | |
| SCHEMBL986215 | 0.76 | ESR2 (0.68) | ESR1ESR2MEN1KMT2A | |
| SCHEMBL6547544 | 0.76 | ESR1 (0.50) | ESR1ESR2IDO1HPGDKMT2A | |
| SCHEMBL20033062 | 0.76 | C1S (0.46) | HPGDMEN1LMNAALOX12KMT2A | |
| SCHEMBL12336908 | 0.75 | ESR2 (0.78) | ESR1ESR2MEN1LMNAKMT2A | |
| SCHEMBL29343067 | 0.75 | ESR2 (0.46) | ESR1ESR2LMNASMN1; SMN2 | |
| SCHEMBL14744545 | 0.75 | ESR1 (0.46) | ESR1ESR2IDO1TDO2KMT2A | |
| SCHEMBL12076821 | 0.73 | MEN1 (0.66) | HPGDMEN1KMT2AGAANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10196406-B2 | Process for the preparation of aminoaryl- and aminoheteroaryl boronic acids and esters | EUTICALS S.P.A. (IT) | 2019-02-05 | — | — | US | disclosed |
| US-20170305937-A1 | PROCESS FOR THE PREPARATION OF AMINOARYL- AND AMINOHETEROARYL BORONIC ACIDS AND ESTERS | AMRI ITALY S.R.L. (IT) | 2017-10-26 | — | — | US | disclosed |
| US-9738663-B2 | Process for the preparation of aminoaryl- and aminoheteroaryl boronic acids and esters | EUTICALS S.P.A. (IT) | 2017-08-22 | — | — | US | disclosed |
| EP-2994473-B1 | PROCESS FOR THE PREPARATION OF AMINOARYL- AND AMINOHETEROARYL BORONIC ACIDS AND ESTERS | EUTICALS SPA (IT) | 2016-12-21 | — | — | EP | disclosed |
| US-20160075723-A1 | PROCESS FOR THE PREPARATION OF AMINOARYL- AND AMINOHETEROARYL BORONIC ACIDS AND ESTERS | AMRI ITALY S.R.L. (IT) | 2016-03-17 | — | — | US | disclosed |
| EP-2801577-A1 | Process for the preparation of aminoaryl- and aminoheteroaryl boronic acids and esters | Euticals S.P.A. (IT) | 2014-11-12 | — | — | EP | disclosed |
| US-20080269523-A1 | Preparation of Aminoaryl and Aminoheteroaryl Boronic Acids and Derivatives Thereof | ARCHIMICA GMBH (DE) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269523-A1 | Preparation of Aminoaryl and Aminoheteroaryl Boronic Acids and Derivatives Thereof | BCAT1, BCAT2, AADAT | ESR1 2053/4885ESR2 2415/4885IDO1 889/4885 |
| US-10196406-B2 | Process for the preparation of aminoaryl- and aminoheteroaryl boronic acids and esters | AADAT, BCAT2, BCAT1 | ESR1 1272/4885ESR2 1338/4885IDO1 1196/4885 |
| US-20170305937-A1 | PROCESS FOR THE PREPARATION OF AMINOARYL- AND AMINOHETEROARYL BORONIC ACIDS AND ESTERS | AADAT, BCAT2, BCAT1 | ESR1 1272/4885ESR2 1338/4885IDO1 1196/4885 |
| US-20160075723-A1 | PROCESS FOR THE PREPARATION OF AMINOARYL- AND AMINOHETEROARYL BORONIC ACIDS AND ESTERS | AADAT, BCAT2, BCAT1 | ESR1 1900/4885ESR2 2049/4885IDO1 395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.