Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 3/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38662990 | 0.85 | KDM4E (0.54) | KDM4EALOX15TSHRSIRT1POLB | |
| SCHEMBL5191836 | 0.75 | ITGB3 (0.52) | KDM4EALOX15TSHRSIRT1POLB | |
| SCHEMBL29676908 | 0.75 | KDM4E (0.71) | KDM4EALOX15TSHRSIRT1KMT2A | |
| Hydrochloric Acid SCHEMBL7399479 | 0.75 | ALDH1A1 (0.58) | KDM4EALOX15POLBKMT2AMAPT | |
| SCHEMBL311850 | 0.75 | KDM4E (0.71) | KDM4EALOX15TSHRSIRT1KMT2A | |
| Hydrochloric Acid SCHEMBL1374318 | 0.75 | ALDH1A1 (0.58) | KDM4EALOX15POLBKMT2AMAPT | |
| Hydrochloric Acid SCHEMBL1371861 | 0.74 | NOTUM (0.45) | KDM4EALOX15KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL29456062 | 0.73 | POLB (0.64) | KDM4EPOLBCYP2C9CYP2C19KMT2A | |
| SCHEMBL12153004 | 0.73 | CYP2A6 (0.40) | POLBKMT2AHSD17B3 | |
| SCHEMBL933584 | 0.73 | POLB (0.64) | KDM4EPOLBCYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010034041-A1 | PEPTIDES AND PEPTIDOMIMETIC COMPOUNDS, THE MANUFACTURING THEREOF AS WELL AS THEIR USE FOR PREPARING A THERAPEUTICALLY AND/OR PREVENTIVELY ACTIVE PHARMACEUTICAL COMPOSITION | FIBREX MEDICAL RESEARCH & DEVELOPMENT GMBH (AT) | 2010-04-01 | — | — | WO | disclosed |
| EP-0994892-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999007732-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 1999-02-18 | — | — | WO | disclosed |