Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16242531 | 0.75 | THRB (0.34) | TDP1THRBMEN1MAPTHTT | |
| SCHEMBL30530260 | 0.74 | TDP1 (0.42) | TDP1THRBMEN1MAPTHTT | |
| SCHEMBL15378096 | 0.73 | CYP3A4 (0.38) | TDP1THRBMEN1MAPTHTT | |
| SCHEMBL8611470 | 0.72 | THRB (0.32) | TDP1THRBMEN1MAPTHTT | |
| SCHEMBL12910189 | 0.70 | MAPT (0.34) | TDP1THRBMEN1MAPTHTT | |
| SCHEMBL27569835 | 0.70 | TDP1 (0.39) | TDP1THRBMEN1MAPTHTT | |
| SCHEMBL8734318 | 0.69 | PDK2 (0.37) | MEN1MAPTKMT2AKDM4EMAPK1 | |
| SCHEMBL24701899 | 0.68 | TDP1 (0.39) | TDP1THRBMEN1MAPTHTT | |
| SCHEMBL1615553 | 0.68 | RXRA (0.46) | MEN1KMT2ACYP3A4CYP1A2MAPK1 | |
| SCHEMBL4711277 | 0.68 | BCHE (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879223-B1 | AROMATIC POLYCYCLIC RETINOID-TYPE DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF FOR MAKING PHARMACEUTICAL AND COSMETIC COMPOSITIONS | CT EUROP DE BIOPROSPECTIVE CEB (FR) | 2001-11-07 | — | — | EP | disclosed |
| US-6265423-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE EUROPEEN DE BIOPROSPECTIVE-CEB (FR) | 2001-07-24 | — | — | US | disclosed |
| EP-0137010-A4 | NAPHTHYL OR TETRAHYDRONAPHTHYL-SUBSTITUTED NAPHTHOIC ACID AND DE RIVATES. | STANFORD RES INST INT (US) | 1985-08-12 | — | — | EP | disclosed |
| EP-0137010-A1 | NAPHTHYL OR TETRAHYDRONAPHTHYL-SUBSTITUTED NAPHTHOIC ACID AND DE RIVATES | SRI INTERNATIONAL (US) | 1985-04-17 | — | — | EP | disclosed |
| WO-1984003505-A1 | NAPHTHYL OR TETRAHYDRONAPHTHYL-SUBSTITUTED NAPHTHOIC ACID AND DE RIVATES | STANFORD RES INST INT (US) | 1984-09-13 | — | — | WO | disclosed |