Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 17/20 | 0.42 |
| ▸ | RARB | P10826 | 7/20 | 0.40 |
| ▸ | RARG | P13631 | 7/20 | 0.40 |
| ▸ | RARA | P10276 | 5/20 | 0.40 |
| ▸ | RXRB | P28702 | 9/20 | 0.33 |
| ▸ | RXRG | P48443 | 9/20 | 0.33 |
| ▸ | HNF4A | P41235 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7931988 | 0.86 | RXRA (0.40) | RXRARARBRARGRARARXRB | |
| SCHEMBL7922997 | 0.83 | RXRA (0.52) | RXRARARBRARGRARARXRB | |
| SCHEMBL7941372 | 0.80 | RXRA (0.43) | RXRARARBRARGRARARXRB | |
| SCHEMBL7931172 | 0.75 | RXRA (0.70) | RXRARARBRARGRARARXRB | |
| SCHEMBL7922983 | 0.74 | RXRA (0.43) | RXRARARBRARGRARARXRB | |
| SCHEMBL7923059 | 0.71 | RXRA (0.55) | RXRARARBRARGRARARXRB | |
| SCHEMBL13479212 | 0.71 | RXRA (0.61) | RXRARARBRARGRARARXRB | |
| SCHEMBL7929406 | 0.70 | RXRA (0.38) | RXRAHNF4A | |
| SCHEMBL7923000 | 0.70 | RXRA (0.49) | RXRARARBRARGRARARXRB | |
| SCHEMBL13480473 | 0.69 | RXRA (0.63) | RXRARARBRARGRARARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879223-B1 | AROMATIC POLYCYCLIC RETINOID-TYPE DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF FOR MAKING PHARMACEUTICAL AND COSMETIC COMPOSITIONS | CT EUROP DE BIOPROSPECTIVE CEB (FR) | 2001-11-07 | — | — | EP | disclosed |
| EP-0879223-A1 | AROMATIC POLYCYCLIC RETINOID-TYPE DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF FOR MAKING PHARMACEUTICAL AND COSMETIC COMPOSITIONS | Centre Europeen de Bioprospective -CEB (FR) | 1998-11-25 | — | — | EP | disclosed |
| WO-1997026237-A1 | AROMATIC POLYCYCLIC RETINOID-TYPE DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF FOR MAKING PHARMACEUTICAL AND COSMETIC COMPOSITIONS | CENTRE EUROPEEN DE BIOPROSPECTIVE - CEB (FR) | 1997-07-24 | — | — | WO | disclosed |