Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 13/20 | 0.43 |
| ▸ | HNF4A | P41235 | 3/20 | 0.33 |
| ▸ | RXRB | P28702 | 7/20 | 0.32 |
| ▸ | RXRG | P48443 | 7/20 | 0.32 |
| ▸ | RARA | P10276 | 6/20 | 0.32 |
| ▸ | RARB | P10826 | 6/20 | 0.32 |
| ▸ | RARG | P13631 | 6/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7931062 | 0.84 | RXRA (0.40) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7931172 | 0.79 | RXRA (0.70) | RXRAHNF4ARXRBRXRGRARA | |
| SCHEMBL7931982 | 0.74 | RXRA (0.42) | RXRAHNF4ARXRBRXRGRARA | |
| SCHEMBL7929406 | 0.74 | RXRA (0.38) | RXRAHNF4A | |
| SCHEMBL7922997 | 0.73 | RXRA (0.52) | RXRAHNF4ARXRBRXRGRARA | |
| SCHEMBL7929331 | 0.71 | RARB (0.38) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7929330 | 0.71 | RARB (0.38) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7941372 | 0.70 | RXRA (0.43) | RXRAHNF4ARXRBRXRGRARA | |
| SCHEMBL3185896 | 0.69 | RXRA (0.67) | RXRARXRBRXRGRARARARB | |
| SCHEMBL9484150 | 0.68 | RXRA (0.42) | RXRARXRBRXRGRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879223-B1 | AROMATIC POLYCYCLIC RETINOID-TYPE DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF FOR MAKING PHARMACEUTICAL AND COSMETIC COMPOSITIONS | CT EUROP DE BIOPROSPECTIVE CEB (FR) | 2001-11-07 | — | — | EP | disclosed |
| US-6265423-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE EUROPEEN DE BIOPROSPECTIVE-CEB (FR) | 2001-07-24 | — | — | US | disclosed |