Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 9/20 | 0.35 |
| ▸ | CNR1 | P21554 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GPR18 | Q14330 | 2/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3067221 | 0.94 | NPC1 (0.43) | NPC1RAB9APOLBHSPA5LMNA | |
| SCHEMBL551721 | 0.89 | HSPA5 (0.45) | NPC1RAB9APOLBHSPA5LMNA | |
| SCHEMBL7931282 | 0.88 | NPC1 (0.51) | NPC1RAB9APOLBHSPA5LMNA | |
| SCHEMBL3072179 | 0.88 | CNR1 (0.39) | NPC1RAB9APOLBCNR2CNR1 | |
| SCHEMBL7932014 | 0.87 | NPC1 (0.50) | NPC1RAB9APOLBHSPA5LMNA | |
| SCHEMBL3077136 | 0.85 | CNR1 (0.37) | NPC1RAB9APOLBCNR2CNR1 | |
| SCHEMBL6153043 | 0.84 | HSPA5 (0.60) | NPC1RAB9APOLBHSPA5LMNA | |
| SCHEMBL258641 | 0.84 | CNR1 (0.41) | NPC1RAB9APOLBLMNACNR2 | |
| SCHEMBL3078801 | 0.83 | CNR1 (0.37) | NPC1RAB9APOLBCNR2CNR1 | |
| SCHEMBL3082225 | 0.82 | NPC1 (0.47) | NPC1RAB9APOLBHSPA5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095956-A2 | Thermoset Polyurethane resin and method for the production thereof | Mitsui Chemicals, Inc. (JP) | 2001-05-02 | — | — | EP | disclosed |