SCHEMBL7932084

SCHEMBL7932084

CCCCC1=Cc2ccccc2C1c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
TSHR P16473 1/20 0.35
CYP2C19 P33261 1/20 0.35
LMNA P02545 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
KDM1A O60341 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
LTA4H P09960 1/20 0.32
PPARG P37231 3/20 0.31
CYSLTR2 Q9NS75 2/20 0.31
CYSLTR1 Q9Y271 2/20 0.31
GAA P10253 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28237677 0.81 KDM1A (0.34) KDM1AMAOBGAAL3MBTL1
SCHEMBL815618 0.78 BCHE (0.35) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL29213166 0.78 BCHE (0.35) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL10644406 0.77 TSHR (0.36) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
Hydrochloric Acid SCHEMBL813274 0.77 BCHE (0.34) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL6056009 0.77 BCHE (0.34) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL18242642 0.77 CYP3A4 (0.36) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL11590486 0.77 BCHE (0.34) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
Fluoride Ion SCHEMBL1131501 0.77 BCHE (0.34) CYP3A4CYP2D6CYP2C9TSHRCYP2C19
SCHEMBL2938495 0.76 RET (0.36) CYP3A4CYP2D6CYP2C9TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1082363-A1 ORGANOMETAL COMPOUND, CATALYST SYSTEM CONTAINING SAID ORGANOMETAL COMPOUND AND ITS USE Basell Polyolefine GmbH (DE) 2001-03-14 EP disclosed
WO-2000044799-A1 ORGANOMETAL COMPOUND, CATALYST SYSTEM CONTAINING SAID ORGANOMETAL COMPOUND AND ITS USE TARGOR GMBH (DE) 2000-08-03 WO disclosed