Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | CETP | P11597 | 5/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 3/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7932271 | 1.00 | AKR1C3 (0.42) | AKR1C3CETPMAPK14FFAR1KDM4E | |
| SCHEMBL9804383 | 0.93 | CETP (0.41) | AKR1C3CETPMAPK14FFAR1FFAR4 | |
| SCHEMBL9804381 | 0.93 | CETP (0.41) | AKR1C3CETPMAPK14FFAR1FFAR4 | |
| SCHEMBL9804518 | 0.92 | PPARG (0.44) | CETPMAPK14FFAR1ALDH1A1LMNA | |
| SCHEMBL9804529 | 0.92 | PPARG (0.44) | CETPMAPK14FFAR1ALDH1A1LMNA | |
| SCHEMBL9804369 | 0.92 | PPARD (0.44) | AKR1C3CETPMAPK14FFAR1SMN1; SMN2 | |
| SCHEMBL9804475 | 0.92 | MAPK14 (0.47) | CETPMAPK14FDFT1 | |
| SCHEMBL9804470 | 0.92 | MAPK14 (0.47) | CETPMAPK14FDFT1 | |
| SCHEMBL9804377 | 0.92 | PPARD (0.44) | AKR1C3CETPMAPK14FFAR1SMN1; SMN2 | |
| SCHEMBL9804320 | 0.91 | KDM4E (0.48) | CETPMAPK14KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37087-E1 | 1-(4-ETHOXYPHENYL)-4-(4-FLUORO-3-PHENOXYPHENYL)-1 -TRIFLUOROMETHYLBUTANE OR 1-(4-ETHOXY-3-FLUOROPHENYL)-4-(3-PHENOXYPHENYL)-1-TRIFLUOROMETHYLBUTANE, FOR EXAMPLE; COMBATS INSECTS AND MITES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | disclosed |
| EP-0233834-B1 | INSECTICIDAL TRIFLUORMETHYL ALKANE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-04-22 | — | — | EP | disclosed |
| US-4791123-A | MITICIDES | SCHERING AKT. (DE) | 1988-12-13 | — | — | US | disclosed |
| EP-0233834-A1 | Insecticidal trifluormethyl alkane derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-08-26 | — | — | EP | disclosed |