Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | CETP | P11597 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | FDFT1 | P37268 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804377 | 1.00 | PPARD (0.44) | PPARDMAPK14CETPSMN1; SMN2FFAR1 | |
| SCHEMBL7932267 | 0.92 | AKR1C3 (0.42) | MAPK14CETPSMN1; SMN2FFAR1AKR1C3 | |
| SCHEMBL7932271 | 0.92 | AKR1C3 (0.42) | MAPK14CETPSMN1; SMN2FFAR1AKR1C3 | |
| SCHEMBL9804383 | 0.89 | CETP (0.41) | MAPK14CETPFFAR1AKR1C3FFAR4 | |
| SCHEMBL9804381 | 0.89 | CETP (0.41) | MAPK14CETPFFAR1AKR1C3FFAR4 | |
| SCHEMBL9804470 | 0.88 | MAPK14 (0.47) | PPARDMAPK14CETPFDFT1 | |
| SCHEMBL9804518 | 0.88 | PPARG (0.44) | MAPK14CETPFFAR1FDFT1 | |
| SCHEMBL9804475 | 0.88 | MAPK14 (0.47) | PPARDMAPK14CETPFDFT1 | |
| SCHEMBL9804529 | 0.88 | PPARG (0.44) | MAPK14CETPFFAR1FDFT1 | |
| SCHEMBL9804320 | 0.87 | KDM4E (0.48) | MAPK14CETPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| US-4791139-A | Diphenyl ether derivatives and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-13 | — | — | US | disclosed |