Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 3/20 | 0.62 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | TNF | P01375 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlormidazole SCHEMBL148113 | 0.78 | GALR3 (1.00) | GALR3NR2F2RAB9ATNFNPSR1 | |
| Chlormidazole SCHEMBL30402878 | 0.78 | GALR3 (1.00) | GALR3NR2F2RAB9ATNFNPSR1 | |
| Chlormidazole SCHEMBL364033 | 0.76 | GALR3 (0.97) | GALR3NR2F2RAB9ATNFNPSR1 | |
| SCHEMBL6833621 | 0.76 | TNF (0.81) | GALR3NR2F2RAB9ATNFNPSR1 | |
| SCHEMBL231295 | 0.76 | TNF (1.00) | GALR3NR2F2RAB9ATNFHDAC1 | |
| SCHEMBL3974900 | 0.74 | TNF (0.77) | GALR3NR2F2RAB9ATNFHDAC1 | |
| SCHEMBL12771519 | 0.74 | GALR3 (1.00) | GALR3NR2F2RAB9ATNFNPSR1 | |
| SCHEMBL8320197 | 0.74 | TNF (0.77) | GALR3NR2F2RAB9ATNFHDAC1 | |
| SCHEMBL8220572 | 0.74 | TNF (0.77) | GALR3NR2F2RAB9ATNFHDAC1 | |
| SCHEMBL9260111 | 0.74 | TNF (0.77) | GALR3NR2F2RAB9ATNFHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248738-B1 | ANTIULCER AGENTS, ANGIOGENESIS INHIBITORS, ANTIMETASTASIS AGENTS, ANTITUMOR AGENTS | PFIZER INC. | 2001-06-19 | — | — | US | disclosed |