SCHEMBL7932427

SCHEMBL7932427

CCOc1ccccc1Oc1ccccc1C(N)=O

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
LMNA P02545 2/20 0.60
MAPT P10636 2/20 0.60
NR1I2 O75469 1/20 0.60
CHRM2 P08172 1/20 0.60
CYP3A4 P08684 1/20 0.60
ADRA2A P08913 1/20 0.60
OPRK1 P41145 1/20 0.60
HTR2B P41595 1/20 0.60
SLC6A3 Q01959 1/20 0.60
HDAC6 Q9UBN7 1/20 0.60
CTNNB1 P35222 1/20 0.57
GLA P06280 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
HTT P42858 2/20 0.53
IRAK4 Q9NWZ3 1/20 0.51
HCRTR1 O43613 2/20 0.51
HPGD P15428 1/20 0.49
KDM4E B2RXH2 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethenzamide SCHEMBL25624 0.90 MAPT (0.68) MEN1KMT2ALMNAMAPTNR1I2
Ethenzamide SCHEMBL27612766 0.90 MAPT (0.68) MEN1KMT2ALMNAMAPTNR1I2
Ethenzamide SCHEMBL4379591 0.88 MAPT (0.66) MEN1KMT2ALMNAMAPTNR1I2
Ethenzamide SCHEMBL22163775 0.88 MAPT (0.66) MEN1KMT2ALMNAMAPTNR1I2
Ethenzamide SCHEMBL5401172 0.88 MAPT (0.66) MEN1KMT2ALMNAMAPTNR1I2
SCHEMBL17454086 0.85 HTT (0.67) MEN1KMT2ALMNAMAPTGLA
SCHEMBL5936606 0.84 CTNNB1 (0.68) MEN1KMT2ALMNAMAPTNR1I2
SCHEMBL7693879 0.84 CTNNB1 (0.77) MEN1KMT2ALMNAMAPTNR1I2
Ethenzamide SCHEMBL5382992 0.83 MAPT (0.60) MEN1KMT2ALMNAMAPTNR1I2
SCHEMBL5175230 0.82 HTT (0.73) MEN1KMT2ALMNAMAPTNR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1104232-A2 HERBICIDES Aventis CropScience GmbH (DE) 2001-06-06 EP disclosed
WO-2000003591-A2 HERBICIDES AVENTIS CROPSCIENCE GMBH (DE) 2000-01-27 WO disclosed