Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759551 | 0.81 | MAOB (0.42) | ELANEKMT2AMEN1CYP1A2ALDH1A1 | |
| SCHEMBL7761136 | 0.79 | ELANE (0.73) | ELANEALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11758974 | 0.77 | ELANE (0.54) | ELANEKMT2AMEN1CYP1A2ALDH1A1 | |
| SCHEMBL3141164 | 0.74 | LMNA (0.63) | ELANEKMT2AMEN1CYP1A2ALDH1A1 | |
| SCHEMBL30239922 | 0.74 | LMNA (0.63) | ELANEKMT2AMEN1CYP1A2ALDH1A1 | |
| SCHEMBL21357271 | 0.74 | CYP1A2 (0.56) | KMT2AMEN1CYP1A2ALDH1A1NPC1 | |
| SCHEMBL8589792 | 0.72 | ELANE (0.64) | ELANEALDH1A1RAB9ACYP3A4MAPK1 | |
| SCHEMBL16954924 | 0.70 | LMNA (0.54) | ELANEKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL26802232 | 0.70 | NPC1 (0.56) | KMT2AMEN1CYP1A2ALDH1A1NPC1 | |
| SCHEMBL803825 | 0.70 | KMT2A (0.53) | KMT2AMEN1CYP1A2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245922-B1 | PREPARED BY REACTING AN ELECTROPHILIC 2-ALKENYL AZALACTONE WITH A NUCLEOPHILIC AROMATIC KETONE; CAN BE COPOLYMERIZED WITH ACRYLIC MONOMERS AND PHOTOACTIVATED BY ACTINIC RADIATION TO CROSSLINK THE POLYMERS | 3M INNOVATIVE PROPERTIES COMPANY | 2001-06-12 | — | — | US | disclosed |
| EP-0837844-B1 | ACRYLAMIDE DERIVATIVES AS CHROMOPHORIC PHOTOCROSSLINKING COMPOUND | MINNESOTA MINING & MFG (US) | 2000-04-05 | — | — | EP | disclosed |