SCHEMBL7932475

SCHEMBL7932475

O=C(Oc1cccc(Cl)c1)C(=O)Oc1cccc(Cl)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.51
OGG1 O15527 1/20 0.49
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
RXRA P19793 1/20 0.47
RXRB P28702 1/20 0.47
RXRG P48443 1/20 0.47
KDM4E B2RXH2 3/20 0.46
USP2 O75604 1/20 0.46
ALDH1A1 P00352 1/20 0.46
ALOX15 P16050 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
WDR5 P61964 1/20 0.46
PARP1 P09874 1/20 0.45
FAAH O00519 1/20 0.44
FFAR1 O14842 1/20 0.44
PPARG P37231 1/20 0.44
PPARD Q03181 1/20 0.44
LMNA P02545 1/20 0.44
NPC1 O15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5790568 0.88 OGG1 (0.47) BCHEOGG1KMT2AMEN1RXRA
SCHEMBL28818350 0.88 KDM4E (0.49) BCHEOGG1KMT2AMEN1RXRA
SCHEMBL5916715 0.87 BCHE (0.51) BCHEOGG1KMT2AMEN1RXRA
SCHEMBL11126845 0.85 BCHE (0.48) BCHEOGG1KMT2AMEN1RXRA
SCHEMBL4903615 0.85 ELANE (0.49) BCHEOGG1KMT2AMEN1RXRA
SCHEMBL9671211 0.85 BCHE (0.50) BCHEOGG1KMT2AMEN1RXRA
SCHEMBL9671217 0.85 RXRA (0.50) BCHEOGG1KMT2AMEN1RXRA
SCHEMBL3884023 0.85 BCHE (0.50) BCHEOGG1KMT2AMEN1RXRA
SCHEMBL4344412 0.85 BCHE (0.50) BCHEOGG1KMT2AMEN1RXRA
SCHEMBL28051255 0.84 OGG1 (0.55) BCHEOGG1KMT2AMEN1RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0834496-B1 Preparation of diaryl carbonate UBE INDUSTRIES (JP) 2001-08-16 EP disclosed
EP-0834495-B1 Process for preparing diaryl carbonate UBE INDUSTRIES (JP) 2000-12-27 EP disclosed
US-5892089-A FROM DIARYL OXALATE IN LIQUID PHASE BY DECARBONYLATION USING ORGANIC PHOSHORUS COMPOUND CATALYST UBE INDUSTRIES, LTD. (JP) 1999-04-06 US disclosed
US-5792883-A Preparation of diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1998-08-11 US disclosed
EP-0834496-A1 Preparation of diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1998-04-08 EP disclosed
EP-0834495-A1 Process for preparing diaryl carbonate UBE INDUSTRIES, LTD. (JP) 1998-04-08 EP disclosed