Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27513160 | 0.85 | FYN (0.35) | ADORA1KDRFYN | |
| Hydrochloric Acid SCHEMBL27513161 | 0.85 | NPC1 (0.35) | HTR1AHTR7KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3163965 | 0.83 | PDCD1 (0.35) | HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL29424591 | 0.83 | PDCD1 (0.35) | HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL5709184 | 0.83 | PDCD1 (0.35) | HTR1AHTR7 | |
| SCHEMBL27486140 | 0.81 | ESR2 (0.40) | ESR2DHFRHTR1AHTR7TP53 | |
| Hydrochloric Acid SCHEMBL28878594 | 0.81 | BRD4 (0.32) | — | |
| Hydrochloric Acid SCHEMBL27495381 | 0.81 | PDCD1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL28742919 | 0.81 | — | — | |
| Iodide SCHEMBL28815111 | 0.80 | PDCD1 (0.35) | HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010014718-A1 | RESIN COMPOSITIONS AND USE OF THE SAME | MITSUI CHEMICALS, INC. (JP) | 2001-08-16 | — | — | US | disclosed |
| CN-1217685-A | VULCANIZED MOLDING HAVING SURFACE DECORATIVE LAYER, PAINTED THERMOPLASTIC RESIN COMPOSITION AND PAINTED ELASTOMER COMPOSITION | MITSUI CHEMICALS INC (JP) | 1999-05-26 | — | — | CN | disclosed |
| CN-1216055-A | RUBBER COMPOSITIONS FOR TIRES | MITSUI CHEMICALS INC (JP) | 1999-05-05 | — | — | CN | disclosed |
| CN-1216053-A | SHRINKABLE FILM MADE FROM OLEFINE COPOLYMER | MITSUI CHEMICALS INC (JP) | 1999-05-05 | — | — | CN | disclosed |