SCHEMBL27486140

SCHEMBL27486140

CC1=Cc2c(-c3cccc(Cl)c3)cccc2C1[Zr]

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.40
DHFR P00374 1/20 0.36
HTR1A P08908 1/20 0.36
HTR7 P34969 1/20 0.36
TP53 P04637 1/20 0.35
TDO2 P48775 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
PGR P06401 1/20 0.33
CA12 O43570 1/20 0.33
CA9 Q16790 1/20 0.33
PTAFR P25105 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
IKBKE Q14164 1/20 0.33
ALOX5 P09917 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27485115 0.85 CHEK1 (0.35) ADORA1NPC1RAB9ASMN1; SMN2ALDH1A1
Chloromethane SCHEMBL5722647 0.83 PDCD1 (0.34)
SCHEMBL4603520 0.83 PDCD1 (0.36) HTR1AHTR7ALDH1A1
Hydrochloric Acid SCHEMBL28723777 0.81 PDCD1 (0.35) HTR1AHTR7TP53RAB9AALDH1A1
Hydrochloric Acid SCHEMBL5695379 0.81 PDCD1 (0.35) HTR1AHTR7TP53RAB9AALDH1A1
Hydrochloric Acid SCHEMBL7932490 0.81 ESR2 (0.39) ESR2DHFRHTR1AHTR7TP53
SCHEMBL7932491 0.80 ESR2 (0.38) ESR2DHFRHTR1AHTR7TP53
SCHEMBL27485116 0.80 EDNRB (0.34) NPC1RAB9AALDH1A1
Hydrochloric Acid SCHEMBL28878595 0.79 BRD4 (0.32)
SCHEMBL27474790 0.79 ADRA2A (0.35) HTR1AHTR7ADORA2AADORA1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1171097-A Norbornene compound having chain polyene group and unsaturated ethylene copolymer prepared using the same MITSUI PETROCHEMICAL IND (JP) 1998-01-21 CN disclosed