Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9362849 | 0.92 | ALDH1A1 (0.46) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL7058356 | 0.91 | ALDH1A1 (0.50) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL8654680 | 0.86 | ALDH1A1 (0.44) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL7107572 | 0.82 | ALOX15 (0.43) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL18898882 | 0.81 | ALDH1A1 (0.40) | ALDH1A1SOAT1LMNAHSD17B10MEN1 | |
| SCHEMBL13457064 | 0.79 | ALDH1A1 (0.52) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL18898881 | 0.78 | ALDH1A1 (0.38) | ALDH1A1SOAT1SMN1; SMN2 | |
| SCHEMBL12334684 | 0.77 | ALDH1A1 (0.50) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL1670811 | 0.77 | ALDH1A1 (0.50) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL6898926 | 0.76 | ALDH1A1 (0.48) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873984-B1 | Process for preparing alkyl- and aryl- substituted malonic acids | DEGUSSA (DE) | 2001-09-12 | — | — | EP | disclosed |
| EP-0857712-B1 | Process for the preparation of cyclopropane-1,1-dicarboxylic acid | DEGUSSA (DE) | 2001-07-18 | — | — | EP | disclosed |
| EP-0873984-A1 | Process for preparing alkyl- and aryl- substituted malonic acids | HÜLS AKTIENGESELLSCHAFT (DE) | 1998-10-28 | — | — | EP | disclosed |
| EP-0857712-A1 | Process for the preparation of malonic and alkylmalonic acids | HÜLS AKTIENGESELLSCHAFT (DE) | 1998-08-12 | — | — | EP | disclosed |
| EP-0459285-B1 | Ortho-substituted benzyl esters of cyclopropane carboxylic acids | BASF AG (DE) | 1994-12-14 | — | — | EP | disclosed |
| EP-0459285-A1 | Ortho-substituted benzyl esters of cyclopropane carboxylic acids | BASF Aktiengesellschaft (DE) | 1991-12-04 | — | — | EP | disclosed |