SCHEMBL7932867

SCHEMBL7932867

N#CC(C#N)(CCC(=O)O)CCC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.40
EGLN1 Q9GZT9 2/20 0.40
ALKBH5 Q6P6C2 1/20 0.40
SUCNR1 Q9BXA5 1/20 0.40
KMT2A Q03164 3/20 0.37
CYP1A2 P05177 3/20 0.37
ALDH1A1 P00352 2/20 0.37
THRB P10828 2/20 0.37
MEN1 O00255 1/20 0.37
SLC22A6 Q4U2R8 1/20 0.36
NAALAD2 Q9Y3Q0 1/20 0.35
TSHR P16473 3/20 0.35
NFKB1 P19838 1/20 0.35
PMP22 Q01453 1/20 0.35
HDAC3 O15379 2/20 0.33
HDAC1 Q13547 2/20 0.33
HDAC2 Q92769 2/20 0.33
HDAC8 Q9BY41 2/20 0.33
FFAR3 O14843 1/20 0.33
ESR1 P03372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5146425 0.81
SCHEMBL28702120 0.79 LMNA (0.40) LMNAEGLN1ALKBH5SUCNR1KMT2A
SCHEMBL7932882 0.77 FOLH1 (0.46) NAALAD2
SCHEMBL15504 0.75 NAALAD2 (0.42) LMNAEGLN1ALKBH5SUCNR1KMT2A
SCHEMBL3810810 0.75 ALDH1A1 (0.39) LMNAEGLN1ALKBH5SUCNR1KMT2A
SCHEMBL10783639 0.75 NAALAD2 (0.42) LMNAEGLN1ALKBH5SUCNR1KMT2A
SCHEMBL8856907 0.75 ALDH1A1 (0.39) LMNAEGLN1ALKBH5SUCNR1KMT2A
SCHEMBL20876110 0.73 NAALAD2 (0.41) LMNAEGLN1ALKBH5SUCNR1KMT2A
SCHEMBL28333405 0.72 ALDH1A1 (0.39) LMNAEGLN1ALKBH5SUCNR1ALDH1A1
SCHEMBL21288210 0.72 NAALAD2 (0.39) LMNAEGLN1ALKBH5SUCNR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0618956-B1 POLYFUNCTIONAL MICHAEL ADDITION PRODUCTS AND REFRIGERATION COMPOSITIONS CONTAINING SUCH PRODUCTS ALBEMARLE CORP (US) 2001-07-11 EP disclosed
US-5683618-A MIXTURES OF ESTERS, KETONES OR NITRILES FOR LUBRICANTS FOR STABILITY ALBEMARLE CORPORATION (US) 1997-11-04 US disclosed
US-5569779-A ESTER OILS; LUBRICANTS ALBEMARLE CORPORATION (US) 1996-10-29 US disclosed
US-5430177-A Polyfunctional Michael addition products ALBEMARLE CORPORATION (US) 1995-07-04 US disclosed
US-5391312-A Seal-swell ester oils to counteract seal shrinkage ALBEMARLE CORPORTION (US) 1995-02-21 US disclosed
EP-0618956-A1 POLYFUNCTIONAL MICHAEL ADDITION PRODUCTS AND REFRIGERATION COMPOSITIONS CONTAINING SUCH PRODUCTS ALBEMARLE CORPORATION (US) 1994-10-12 EP disclosed
WO-1993013188-A1 POLYFUNCTIONAL MICHAEL ADDITION PRODUCTS AND REFRIGERATION COMPOSITIONS CONTAINING SUCH PRODUCTS ETHYL CORPORATION (US) 1993-07-08 WO disclosed