SCHEMBL7932871

SCHEMBL7932871

CCCc1nc(CC)c(C(=O)OC)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCCC(C)C)cc1F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 19/20 1.00
AGTR2 P50052 19/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL243788 0.89 AGTR1 (1.00) AGTR1AGTR2
SCHEMBL7406561 0.89 AGTR1 (1.00) AGTR1AGTR2
SCHEMBL245015 0.88 AGTR1 (0.94) AGTR1AGTR2
SCHEMBL7398390 0.87 AGTR1 (0.80) AGTR1AGTR2
SCHEMBL7398393 0.87 AGTR1 (0.76) AGTR1AGTR2
SCHEMBL242202 0.86 AGTR1 (0.80) AGTR1AGTR2
SCHEMBL242909 0.86 AGTR1 (0.88) AGTR1AGTR2
SCHEMBL242134 0.84 AGTR1 (0.82) AGTR1AGTR2
SCHEMBL29486804 0.84 AGTR1 (0.72) AGTR1AGTR2
SCHEMBL6556549 0.84 AGTR1 (0.72) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6218414-B1 ADMINISTERING AN EFFECTIVE AMOUNT OF AN ANGIOTENSIN II ANTAGONIST AND A BENZOFURAN DERIVATIVE WITH ANTIARRHYTHMIC ACTIVITY FOR THERAPY OF CARDIOVASCULAR COMPLAINTS SANOFI (FR) 2001-04-17 US disclosed