SCHEMBL7933236

SCHEMBL7933236

Cc1cccc(Cl)c1Nc1c(F)c(F)c2c(c1F)C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.40
LCK P06239 4/20 0.39
PDK1 Q15118 1/20 0.39
PDK2 Q15119 1/20 0.39
PDK3 Q15120 1/20 0.39
PDK4 Q16654 1/20 0.39
CXCR2 P25025 1/20 0.38
GAA P10253 1/20 0.37
CHRNA7 P36544 5/20 0.36
DHODH Q02127 1/20 0.35
CXCL8 P10145 1/20 0.35
SRC P12931 1/20 0.35
MAPK14 Q16539 1/20 0.34
BCHE P06276 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7929769 0.95 PTGS2 (0.41) PTGS2LCKPDK1PDK2PDK3
SCHEMBL7927149 0.91 PTGS2 (0.39) PTGS2LCKPDK1PDK2PDK3
SCHEMBL7921338 0.90 MAPT (0.37) PTGS2GAACXCL8
SCHEMBL7929777 0.90 CXCR2 (0.42) CXCR2GAADHODH
SCHEMBL7921206 0.87 EGFR (0.41) PTGS2LCK
SCHEMBL6651442 0.85 DHODH (0.42) PTGS2LCKPDK1PDK2PDK3
SCHEMBL7933254 0.84 MAPT (0.39) PTGS2GAACXCL8
SCHEMBL7921267 0.84 CXCR2 (0.44) PTGS2CXCR2GAADHODH
SCHEMBL7927135 0.82 KDM4E (0.45) PTGS2CXCR2DHODH
SCHEMBL7921360 0.81 MAPK14 (0.36) PTGS2LCKCHRNA7MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5968688-A RESINS AND DYES FOR COLOR FILTERS NIPPON SHOKUBAI CO., LTD. (JP) 1999-10-19 US disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
EP-0833203-A1 Color filter grade photosensitive resin coloring composition, and color filter using the same NIPPON SHOKUBAI CO., LTD. (JP) 1998-04-01 EP disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed