SCHEMBL7933237

SCHEMBL7933237

CCCCOc1c(Nc2c(C)cccc2C(=O)OCC)c(Nc2c(C)cccc2C(=O)OCC)c(Cl)c2c1C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METTL3 Q86U44 1/20 0.38
HSD17B10 Q99714 2/20 0.36
USP2 O75604 1/20 0.36
TSHR P16473 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CDC25B P30305 1/20 0.35
THRB P10828 1/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
CA14 Q9ULX7 1/20 0.34
AURKA O14965 1/20 0.34
AURKB Q96GD4 1/20 0.34
ELANE P08246 1/20 0.34
GAA P10253 2/20 0.33
MAPT P10636 2/20 0.33
TP53 P04637 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7927118 0.96 TSHR (0.38) METTL3HSD17B10USP2TSHRCDC25B
SCHEMBL7930692 0.90 USP2 (0.37) HSD17B10USP2TSHRTDP1L3MBTL1
SCHEMBL7929802 0.86 TSHR (0.38) HSD17B10USP2TSHRCDC25BTHRB
SCHEMBL7927286 0.84 THRB (0.38) METTL3HSD17B10USP2TSHRTDP1
SCHEMBL7929882 0.81 ELANE (0.34) HSD17B10USP2TDP1L3MBTL1CDC25B
SCHEMBL7928567 0.81 LMNA (0.36) METTL3TSHRCDC25BTHRBCA12
SCHEMBL7921356 0.80 SMN1; SMN2 (0.48) CDC25BTHRBMAPTTP53CYP2C9
SCHEMBL7921537 0.79 SOAT1 (0.37)
SCHEMBL7928410 0.79 MAPT (0.47) TSHRTHRBCA1CA2MAPT
SCHEMBL7930665 0.78 MAPK14 (0.36) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed