SCHEMBL7933442

SCHEMBL7933442

CCO[Si](CC(C)C(C)C)(OCC)OCC

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7933407 0.92
SCHEMBL7929955 0.87
SCHEMBL7929978 0.83
SCHEMBL7930017 0.83
SCHEMBL104863 0.82 LMNA (0.32) LMNA
SCHEMBL7930013 0.81
SCHEMBL31142050 0.80 LMNA (0.30) LMNA
Ammonia Solution, Strong SCHEMBL29153382 0.80 LMNA (0.30) LMNA
SCHEMBL7936184 0.79 METAP1 (0.34)
Ammonia Solution, Strong SCHEMBL3735754 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160009747-A1 PLATINUM METALLACYCLES COMPRISING N, P, OR AS RINGATOMS AND THEIR USE AS CATALYSTS IN 1,2-HYDROSILYLATION REACTIONS OF DIENES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2016-01-14 US disclosed
EP-0717053-B1 Catalyst for olefin polymerization and process for producing polyolefin using the same JAPAN POLYOLEFINS CO LTD (JP) 2001-03-14 EP disclosed
US-6096844-A COMPRISING A TITANIUM COMPOUND, A MAGNESIUM COMPOUND, AND A HALOGEN COMPOUND, AN ORGANOALUMINUM COMPOUND, AN ORGANOSILICON COMPOUND JAPAN POLYOLEFINS CO., LTD. (JP) 2000-08-01 US disclosed
US-5849654-A Catalyst for olefin polymerization and process for producing polyolefin using the same JAPAN POLYOLEFINS CO., LTD. (JP) 1998-12-15 US disclosed
EP-0717053-A2 Catalyst for olefin polymerization and process for producing polyolefin using the same JAPAN POLYOLEFINS CO., LTD. (JP) 1996-06-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160009747-A1 PLATINUM METALLACYCLES COMPRISING N, P, OR AS RINGATOMS AND THEIR USE AS CATALYSTS IN 1,2-HYDROSILYLATION REACTIONS OF DIENES DHPS, APEX1, POP1 LMNA 2926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.