Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR1 | P47211 | 6/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6309408 | 0.67 | GALR1 (0.45) | GALR1CA12CA9ALDH1A1CA2 | |
| Biphenyl SCHEMBL32685219 | 0.62 | ALDH1A1 (0.90) | ALDH1A1CA2LMNAMAPTHTT | |
| SCHEMBL8986271 | 0.60 | ALDH1A1 (0.47) | GALR1CA12CA9ALDH1A1CFTR | |
| SCHEMBL7212942 | 0.58 | ALDH1A1 (0.53) | ALDH1A1CFTRGOPCLMNAMAPT | |
| Biphenyl SCHEMBL1358618 | 0.58 | ALDH1A1 (1.00) | ALDH1A1CA2LMNAMAPTHTT | |
| SCHEMBL29560186 | 0.58 | ALDH1A1 (1.00) | ALDH1A1CA2LMNAMAPTHTT | |
| Biphenyl SCHEMBL164 | 0.58 | ALDH1A1 (1.00) | ALDH1A1CA2LMNAMAPTHTT | |
| Biphenyl SCHEMBL4002609 | 0.58 | ALDH1A1 (1.00) | ALDH1A1CA2LMNAMAPTHTT | |
| Biphenyl SCHEMBL2548048 | 0.58 | ALDH1A1 (1.00) | ALDH1A1CA2LMNAMAPTHTT | |
| Biphenyl SCHEMBL28890607 | 0.58 | ALDH1A1 (1.00) | ALDH1A1CA2LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242478-B1 | ANTICARCINOGENIC AGENTS; REPLICATION INHIBITORS OF HUMAN LYMPHADENOPATHY ASSOCIATED VIRUS(HIV) | WAKE FOREST UNIVERSITY | 2001-06-05 | — | — | US | disclosed |