Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | GALR1 | P47211 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11659237 | 0.86 | P2RX7 (0.43) | ALDH1A1LMNAMAPTHTTGPR3 | |
| SCHEMBL9351602 | 0.86 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTHTTGPR3 | |
| SCHEMBL6308790 | 0.84 | GPR3 (0.39) | ALDH1A1LMNAMAPTHTTGPR3 | |
| SCHEMBL3627652 | 0.80 | BCL2L1 (0.42) | ALDH1A1LMNAMAPTHTTCA12 | |
| SCHEMBL65330 | 0.77 | CTRC (0.36) | ALDH1A1LMNAMAPTHTTCA12 | |
| SCHEMBL11656759 | 0.77 | PDGFRA (0.38) | ALDH1A1LMNAMAPTHTTCA12 | |
| Biphenyl SCHEMBL32685219 | 0.71 | ALDH1A1 (0.90) | ALDH1A1LMNAMAPTHTTNPC1 | |
| SCHEMBL6309408 | 0.71 | GALR1 (0.45) | ALDH1A1LMNAMAPTHTTGPR3 | |
| Biphenyl SCHEMBL1358618 | 0.67 | ALDH1A1 (1.00) | ALDH1A1LMNAMAPTHTTNPC1 | |
| Biphenyl SCHEMBL164 | 0.67 | ALDH1A1 (1.00) | ALDH1A1LMNAMAPTHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579770-B1 | MACROCYCLIC LACTAM PROKINETIC AGENTS | ABBOTT LAB (US) | 1996-06-26 | — | — | EP | claimed |
| US-5476743-A | Thermoplastic resin, a charge director, a liquid component, an additive selected from cyclic carbonates, cyclic sulfones, cyclic sulfoxides and organic amides, pigments, and a charge adjuvant | XEROX CORPORATION (US) | 1995-12-19 | — | — | US | claimed |
| JP-6194702-A | — | — | None | — | — | JP | disclosed |
| US-5476743-A | Thermoplastic resin, a charge director, a liquid component, an additive selected from cyclic carbonates, cyclic sulfones, cyclic sulfoxides and organic amides, pigments, and a charge adjuvant | XEROX CORPORATION (US) | 1995-12-19 | — | — | US | disclosed |
| US-5434208-A | Calixarenes, hyperpolarizability | AKZO NOBEL N.V. (NL) | 1995-07-18 | — | — | US | disclosed |
| JP-H06194702-A | OPTICALLY NONLINEAR ACTIVE WAVEGUIDE MATERIAL CONTAINING DOPANT HAVING PLURAL DONOR-PI-ACCEPTOR SYSTEMS | AKZO NV | 1994-07-15 | — | — | JP | disclosed |
| EP-0313474-A2 | An optical article exhibiting a high level of second order polarization susceptibility | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-04-26 | — | — | EP | disclosed |